Results 51 to 60 of about 4,399 (136)

Recurrent Steroid‐Responsive Exophthalmos as a Paraneoplastic Manifestation of Esophageal Adenocarcinoma

open access: yesCase Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Exophthalmos is most often associated with autoimmune thyroid disease, particularly Graves disease. Paraneoplastic syndromes rarely manifest as orbital inflammation, and only a few cases have been described in association with solid tumors. We present a case of a 67‐year‐old male diagnosed with esophageal cancer.
Yara E. Tovar   +2 more
wiley   +1 more source

PDGFRα+DPP4+ Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng   +14 more
wiley   +1 more source

Application of Machine Learning to Discriminate Photoreceptor Cell Species in Xenotransplanted Chimeric Retinas

open access: yesClinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Photoreceptor transplantation is being studied to restore visual function in retinal diseases causing blindness, including age‐related macular degeneration, hereditary eye diseases, and traumatic retinopathy. Preclinical studies often involve delivering exogenous human photoreceptor cells into animal models' retinas.
Kang V. Li   +14 more
wiley   +1 more source

Graves′ orbitopathy: Management of difficult cases

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Management of Graves′ ophthalmopathy (GO) is based on three pillars: to stop smoking, to restore and maintain euthyroidism, and to treat the eye changes according to severity and activity of GO.
Wilmar M Wiersinga
doaj   +1 more source

Glymphatic System Dysfunction in Thyroid‐Associated Ophthalmopathy: A Multimodal MRI Study

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.
TAO patients exhibit impaired glymphatic function, with reduced DTI‐ALPS indices and gBOLD‐CSF coupling, but unchanged choroid plexus volume. These alterations correlate with neuropsychological symptoms and sleep disturbances. Restoring glymphatic activity may offer a therapeutic approach to enhance patient outcomes.
Lijie Zhang   +4 more
wiley   +1 more source

Endoscopic Orbital Decompression for Graves’ Orbitopathy – A Vietnam Study

open access: yesClinical Ophthalmology, 2021
Thi My Hanh Pham,1,2 Chien Thang Nguyen,1 Quoc Tung Mai,2 Thi Huong Giang Bui,2 Dung Hoa Do,2 Peter McCluskey,3 Trong Van Pham2 1Department of Ophthalmology, 103 Military Hospital, Hanoi, Vietnam; 2Department of Ophthalmology, Hanoi Medical University ...
Pham TMH   +6 more
doaj  

Graves’ orbitopathy as a rare disease in Europe: a European Group on Graves’ Orbitopathy (EUGOGO) position statement

open access: yesOrphanet Journal of Rare Diseases, 2017
Background Graves’ orbitopathy (GO) is an autoimmune condition, which is associated with poor clinical outcomes including impaired quality of life and socio-economic status.
P. Perros   +23 more
doaj   +1 more source

Evaluation of the Graves’ Orbitopathy-Specific Quality of Life Questionnaire in the Mainland Chinese Population

open access: yesJournal of Ophthalmology, 2019
Purpose. To study the clinical significance of the Graves’ orbitopathy-specific quality of life (GO-QOL) questionnaire in mainland Chinese patients. Methods.
Peng Zeng   +6 more
doaj   +1 more source

The clinical tomographic interconnection in diplopia of patients with Graves' orbitopathy

open access: yesКлиническая и экспериментальная тиреоидология, 2012
There was investigated the relationship between the clinical features of the diplopia in patients with the Graves’ orbitopathy and the specific signs of the orbit obtained by the multi-slice CT scanning in the study.

doaj   +1 more source

Case series of dermopathy in autoimmune thyroid disease [PDF]

open access: yesMedicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"
Graves' disease (GD) is an autoimmune disease that can affect other tissues in addition to the thyroid gland. The clinical manifestations are a result of the impact of TSH receptor antibodies.
Janić Tamara   +8 more
doaj   +1 more source

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