Results 61 to 70 of about 280,326 (218)
Current and Future Treatments for Graves’ Disease and Graves’ Ophthalmopathy
Hormone and Metabolic Research, 2018 The course and pathogenesis of Graves’ disease and Graves’ ophthalmopathy are interdependent, influencing each other’s therapeutic choices. Multiple factors including geographic location, access to medical services, patient and physician preferences ...
A. Kotwal, M. Stan
semanticscholar +1 more source
International Journal of Endocrinology, Volume 2026, Issue 1, 2026.Background Thyroid eye disease (TED) is an autoimmune inflammatory condition linked to thyroid dysfunction, which can result in disfigurement and potential vision loss. Recently, immunomodulatory therapies such as rituximab have demonstrated potential benefit in managing TED.
Ming Lu +3 more
wiley +1 more source
Indian Journal of Endocrinology and Metabolism, 2013 Pulse methylprednisolone therapy is the recommended therapy for moderate to severe and active ophthalmopathy, but high dose pulse methylprednisolone therapy is marred by the chances of fulminant hepatic failure and the high cost of therapy. Dexamethasone
Rajeev Philip +5 more
doaj +1 more source
The thyroid, the eyes and the gut: a possible connection [PDF]
, 2017 Graves’ disease (GD) is an autoimmune disorder responsible for 60–90% of thyrotoxicosis, with an incidence of 1 to 2 cases per 1000 population per year in England.
Covelli, D., Ludgate, Marian Elizabeth
core +2 more sources
Scientific Reports, 2018 Graves’ disease (GD) is an autoimmune disorder that causes the overproduction of thyroid hormones and consequent cascade of systemic metabolism dysfunction. Moreover, Graves’ ophthalmopathy (GO) is the main extrathyroidal manifestation of Graves’ disease
Dong Yoon Ji +8 more
semanticscholar +1 more source
Journal of Ophthalmology, Volume 2026, Issue 1, 2026.Purpose The conversion rate of ocular myasthenia gravis (OMG) to generalized myasthenia gravis (GMG) lacks definitive predictors. Methods This retrospective cohort study analyzed data collected at Siriraj Hospital between January 2007 and December 2019 to identify factors influencing OMG generalization and the time to conversion. The records of 200 OMG
Wanicha Chuenkongkaew +7 more
wiley +1 more source
Postural variation of exophthalmometry in Graves′ ophthalmopathy
Indian Journal of Ophthalmology, 1990 30 patients with Graves′ ophthalmopathy were subjected to exophthalmometry in the upright and supine positions to determine if the difference in exophthalmometer readings in these two situations are significantly different and would help in ...
Asad Rajvardhan +3 more
doaj
Clinical evaluation of Graves ophthalmopathy [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2012 Introduction. Graves ophthalmopathy is an autoimmune disease, which is the consequence of thyroid dysfunction. Ocular manifestations occur in 50% of patients with Graves disease.
Janićijević-Petrović Mirjana A. +5 more
doaj +1 more source
Application of Agents Against Interferon-Gamma-Dependent Chemokines in Immunotherapy [PDF]
, 2015 The CXC chemokine receptor (CXCR) 3 and its chemokines (CXCL9, CXCL10, CXCL11) are involved in the pathogenesis of autoimmune disesases. Under the influence of interferon (IFN) γ, the IFNγ-inducible chemokines are secreted by lymphocytes, and by ...
Antonelli, Alessandro +4 more
core +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng +14 more
wiley +1 more source