Results 111 to 120 of about 1,530,432 (282)

Success Treatment of Severe and Active Graves’ Orbitopathy with Tocilizumab After Thyroidectomy and Maximum Dose of Intravenous Methylprednisolone

open access: yesActa Medica Indonesiana, 2023
We report a woman, 45th year old with Graves’ disease treated with anti-thyroid drug (thiamazole). She came to our clinic with severe and active Graves’ orbitopathy.
Laurentius Aswin Pramono
doaj  

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby   +4 more
wiley   +1 more source

The IL-4 Level among Patients with Autoimmune Thyroiditis in Al-Najaf Governorate, Iraq

open access: yesMedical Journal of Babylon
Background: The study of autoimmune thyroiditis is considered one of the challenges of sustainable development. Autoimmune thyroiditis includes largely cellular and humoral immune responses targeted at the thyroid gland, including Graves thyroiditis and ...
Sarah Hasan Kadhum Al-Huchaimi   +2 more
doaj   +1 more source

Graves’ Disease: Introduction

open access: yes, 2023
AbstractGraves’ disease is a multisystem disorder and the most common autoimmune disease. Fifty percent of patients with Graves’ disease shows orbital involvement, called Graves’ orbitopathy. Although Graves’ orbitopathy is a self-limiting disease, spontaneous improvement can only be awaited in its milder forms.
openaire   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Podgorica: an Urnfield period settlement as part of the Podgorica-Dragomelj ‘twin settlement’ and an Early Iron Age cemetery

open access: yesArheološki Vestnik
The article presents the results of the archaeological investigations conducted at Podgorica. They revealed a settlement considered part of the Podgorica-Dragomelj ‘twin settlement’ that was located at a former streambed and extended across more than 2 ...
Petra Vojaković
doaj   +1 more source

Appropriate Fiscal Policy over the Business Cycle: Proper Stimulus Policies Can Work [PDF]

open access: yes
Fiscal policy has become quite controversial in the post-Keynesian era, the debate over the Obama stimulus package being a contentious recent example.
Philip E. Graves
core  

Laser‐Induced Microfabrication of Carbon Nanostructure: Processing Mechanism and Application for Next‐Generation Battery Technology

open access: yesAdvanced Functional Materials, EarlyView.
The article reviews laser‐processed carbons from various precursors, processing mechanism and their application in advanced batteries. The laser process is chemical free, fast, and scalable, enabling improved battery performance and stability for Li, Na, and Zn battery technologies.
Sujit Deshmukh   +2 more
wiley   +1 more source

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