Results 211 to 220 of about 297,779 (263)

Thyroid eye disease (Graves' orbitopathy): clinical presentation, epidemiology, pathogenesis, and management.

The Lancet Diabetes and Endocrinology
Thyroid eye disease (TED; also known as Graves' orbitopathy), causes swollen extraocular muscles and orbital fat. Mechanistically, TED involves lid retraction, oedema and redness of the eyelids and conjunctiva, proptosis, diplopia, and optic neuropathy ...
W. Wiersinga, Anja K. Eckstein, M. Žarković   +2 more
semanticscholar   +1 more source

Statin Use and the Risk of Graves’ Orbitopathy: A Nationwide Population-Based Cohort Study

Thyroid
Background: Statin use is reported to reduce the risk of Graves’ orbitopathy (GO) in Western populations. However, study regarding the protective effect of statins against GO in Asians with Graves’ disease (GD) is scarce.
Yu-Tsung Chou, Chun-Chieh Lai, Chung-Yi Li, W-C Shen, Yu-Tung Huang, Yi-Lin Wu, Yi-Hsuan Lin, Deng-Chi Yang, Yi-Ching Yang   +8 more
semanticscholar   +1 more source

Monoclonal Antibodies for the Treatment of Graves Orbitopathy: Precision Medicine?

Ophthalmic Plastic and Reconstructive Surgery, 2023
Purpose: To summarize the development, nomenclature, and rationale of the reported use of monoclonal antibodies (Mabs) in Graves Orbitopathy (GO) and to undertake a systematic review of the management of GO with Mabs.
Naiara F. Xavier, Daniela Tavares Lucena, Antonio A. V. Cruz   +2 more
semanticscholar   +1 more source

Ablative Versus Conservative Approach for Hyperthyroidism Treatment in Patients with Graves’ Orbitopathy: A Retrospective Cohort Study

Thyroid
Background: Treatment for Graves’ hyperthyroidism (GH) in patients with Graves’ orbitopathy (GO) remains a topic of debate. This study aimed to investigate the outcome of GO following glucocorticoids, depending on the chosen thyroid treatment.
G. Cosentino, G. Lanzolla, S. Comi, M. N. Maglionico, C. Posarelli, Dalì Antonia Ciampa, F. Menconi, R. Rocchi, F. Latrofa, Michele Figus, F. Santini, Michele Marinò   +11 more
semanticscholar   +1 more source

Statins in Graves Orbitopathy: A New Therapeutic Tool

Ophthalmic Plastic and Reconstructive Surgery, 2023
Purpose: Graves orbitopathy (GO) is the most common extrathyroidal manifestation of Graves disease. Although its pathogenesis is not fully elucidated, GO is commonly considered an autoimmune disease due to loss of self-tolerance against autoantigens ...
Giulia Lanzolla, S. Comi, G. Cosentino, Farzad Pakdel, Michele Marinò   +4 more
semanticscholar   +1 more source

Evaluating Graves’ Orbitopathy

Best Practice & Research Clinical Endocrinology & Metabolism, 2012
Graves' Orbitopathy (GO) is an immune-mediated disorder causing inflammation and expansion of orbital fat and muscle. The resulting spectrum of ocular and orbital changes may cause significant visual and cosmetic morbidity and are graded as disease severity.
openaire   +2 more sources

Graves' orbitopathy: a multidisciplinary approach

The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2021
Orbitopathy is the main extra thyroidal manifestation of Graves' disease. It is a very challenging condition, which requires a cooperation between many specialists (endocrinologists, ophthalmologists, radiologists, radiotherapeutic, orbital surgeons) for an optimal clinical management.
Limone, Paolo P, Mellano, Marco, Ruo Redda, Maria G, Macera, Annalisa, Ferrero, Vittorio, Sellari Franceschini, Stefano, Deandrea, Maurilio   +6 more
openaire   +2 more sources

Quality of life in patients with Graves’ orbitopathy submitted to orbital decompression: comparison between balanced and inferomedial techniques

Arquivos Brasileiros de Oftalmologia
Purpose To compare inferomedial wall orbital decompression to balanced medial plus lateral wall orbital decompression in patients with Graves’ orbitopathy in the inactive phase with regard to exophthalmos reduction and the effects on quality of life ...
Cristiane de Almeida Leite, Thaís de Sousa Pereira, Jeane Chiang, R. Moritz, A. Gonçalves, M. L. R. Monteiro   +5 more
semanticscholar   +1 more source

Graves orbitopathy: a perspective

Nature Reviews Endocrinology, 2009
Advances in the past few years have helped clinicians understand some of the pathogenetic mechanisms of Graves orbitopathy (GO), particularly the role of receptors for TSH and insulin-like growth factor I in the orbit. Optimal treatment strategies have been formulated and published by the European Group on Graves' Orbitopathy, which are hoped to ...
Petros, Perros, Gerasimos E, Krassas
openaire   +2 more sources

Neuroimaging of Graves’ orbitopathy

Best Practice & Research Clinical Endocrinology & Metabolism, 2012
Neuroimaging of Graves' orbitopathy (GO) plays an important role in the differential diagnosis and interdisciplinary management of patients with GO. Orbital imaging is required in unclear or asymmetric proptosis, in suspected optic neuropathy and prior to decompression surgery. Especially computed tomography and magnetic resonance (MR) imaging show the
Wibke, Müller-Forell, George J, Kahaly
openaire   +2 more sources