Results 31 to 40 of about 7,658 (215)
Differential Gene Expression Profiling of Orbital Adipose Tissue in Thyroid Orbitopathy [PDF]
, 2015 Published under a Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode)PURPOSE. We aimed to determine differentially expressed genes relevant to orbital inflammation and orbital fat
Burdon, Kathryn Penelope +11 more
core +1 more source
Exophthalmos in a young woman with no Graves’ disease – a case report of IgG4-related orbitopathy
BMC Ophthalmology, 2018 Background Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy ...
Annamaria Erdei +4 more
doaj +1 more source
Case Reports in Endocrinology, 2020 We describe a case of worsening Graves’ orbitopathy due to immune reconstitution inflammatory syndrome (IRIS) in a 38-year-old HIV-infected male after beginning ART (antiretroviral therapy).
Ravali Nallu +3 more
doaj +1 more source
Orbital lymphoma associated with Graves’ disease: A case report [PDF]
Vojnosanitetski Pregled, 2014 Introduction. The presence of bilateral exophthalmos and palpebral, periorbital edema associated with hyperthyroidism is most often considered as an initial sign of Graves’ ophthalmopathy.
Hajduković Zoran +4 more
doaj +1 more source
The thyroid, the eyes and the gut: a possible connection [PDF]
, 2017 Graves’ disease (GD) is an autoimmune disorder responsible for 60–90% of thyrotoxicosis, with an incidence of 1 to 2 cases per 1000 population per year in England.
Covelli, D., Ludgate, Marian Elizabeth
core +2 more sources
Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]
, 2020 Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter +7 more
core +1 more source
What has changed in thyroid eye disease in the last five years (2020–2025)
European Thyroid JournalBackground: Significant progress has been made in the management of thyroid eye disease (TED), based on the elucidation of important pathogenic mechanisms. This has led to novel therapeutics validated in randomized clinical trials.
Mario Salvi
doaj +1 more source
Archives of Endocrinology and Metabolism, 2020 Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto +4 more
doaj +1 more source
Modeling Graves’ Orbitopathy in Experimental Graves’ Disease [PDF]
Hormone and Metabolic Research, 2015 AbstractGraves’ orbitopathy (GO), also known as thyroid eye disease is an inflammatory disease of the orbital tissue of the eye that arises as a consequence of autoimmune thyroid disease. The central feature of the disease is the production of antibodies to the thyrotropin hormone receptor (TSHR) that modulate the function of the receptor leading to ...
Banga, J P +3 more
openaire +3 more sources
Current Knowledge on Graves’ Orbitopathy [PDF]
Journal of Clinical Medicine, 2020 (1) Background: Graves’ orbitopathy (GO) is an autoimmune inflammation of the orbital tissues and the most common extra-thyroid symptom of Graves’ disease (GD). Mild cases of GO are often misdiagnosed, which prolongs the diagnostic and therapeutic process, leading to exacerbation of the disease. A severe course of GO may cause permanent vision loss. (2)
Katarzyna Gontarz-Nowak +4 more
openaire +2 more sources