Results 61 to 70 of about 8,591 (298)

Sparse Ultrasound Imaging via Manifold Low-Rank Approximation and Non-Convex Greedy Pursuit

open access: yesSensors, 2018
Model-based image reconstruction has improved contrast and spatial resolution in imaging applications such as magnetic resonance imaging and emission computed tomography.
Thiago Alberto Rigo Passarin   +2 more
doaj   +1 more source

Sparsest Input Selection for Controllability of Singular Systems via a Two-Step Greedy Algorithm

open access: yesIEEE Access, 2020
In this paper, the problem of determining the sparsest input matrices to ensure controllability of linear singular systems is investigated. Firstly, it is shown that, determining the sparsest input matrices to ensure reachable controllability or complete
Yan Zhang, Wanhong Zhang
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Computing Effective Mixed Strategies for Protecting Targets in Large-Scale Critical Infrastructure Networks

open access: yesFrontiers in Physics, 2021
Most critical infrastructure networks often suffer malicious attacks, which may result in network failures. Therefore, how to design more robust defense measures to minimize the loss is a great challenge. In recent years, defense strategies for enhancing
Zhen Wang   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Greedy Methods For Simultaneous Sparse Approximation

open access: yes, 2014
Publication in the conference proceedings of EUSIPCO, Lisbon, Portugal ...
Belmerhnia, Leila   +2 more
openaire   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Convergence rate of the data-independent P-greedy algorithm in kernel-based approximation [PDF]

open access: yes, 2017
Kernel-based methods provide flexible and accurate algorithms for the reconstruction of functions from meshless samples. A major question in the use of such methods is the influence of the samples’ locations on the behavior of the approximation, and ...
Santin, G.   +3 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

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