Results 141 to 150 of about 137,035 (279)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Green's Function for Discrete Second-Order Problems with Nonlocal Boundary Conditions

open access: yesBoundary Value Problems, 2011
We investigate a second-order discrete problem with two additional conditions which are described by a pair of linearly independent linear functionals.
Roman Svetlana   +1 more
doaj  

Towards spectral theory of the Nonstationary Schr\"{o}dinger equation with a two-dimensionally perturbed one-dimensional potential

open access: yes, 2004
The Nonstationary Schr\"{o}dinger equation with potential being a perturbation of a generic one-dimensional potential by means of a decaying two-dimensional function is considered here in the framework of the extended resolvent approach.
Boiti, M.   +3 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Learning domain-independent Green’s function for elliptic partial differential equations [PDF]

open access: green
Pawan Negi   +4 more
openalex   +1 more source

Recursive Green’s Function Registration [PDF]

open access: bronze, 2010
Björn Beuthien   +2 more
openalex   +1 more source

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