Results 41 to 50 of about 189,902 (294)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Does Artificial Intelligence (AI) enhance green economy efficiency? The role of green finance, trade openness, and R&D investment

Humanities & Social Sciences Communications
Marine fisheries constitute a crucial component of global green development, where artificial intelligence (AI) plays an essential role in enhancing green economic efficiency associated with marine fisheries.
Qiang Wang, Tingting Sun, Rongrong Li
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Can Artificial Intelligence Enhance Corporate Green Competitiveness? The Roles of Green Strategy, Innovation, and Practices

SAGE Open
Artificial intelligence (AI) has become an important driving force for sustainable development. Based on panel data from China’s A-share listed companies from 2014 to 2023, this study empirically examines the impact and mechanisms of AI on corporate ...
Xiaoling Yang, Mohd Rahimie Abd Karim, Borhan Sareya Abdullah   +2 more
doaj   +1 more source

A study on the impact of artificial intelligence applications on corporate green technological innovation: A mechanism analysis from multiple perspectives

International Review of Economics & Finance
This paper investigates the impact of artificial intelligence (AI) applications on corporate green technological innovation using a comprehensive panel dataset of Chinese A-share listed firms. AI application is measured by constructing a firm-level index
Lusi Chen, Shinan Li, Zhili She
doaj   +1 more source

Research on AI Computational Energy Consumption Optimization and Green AI [PDF]

SHS Web of Conferences
With the rapid development of Artificial Intelligence (AI), many deep learning models have been extensively applied in various fields, and correspondingly, the environmental issues arising from the development of AI have become one of the pressing ...
Xu Jiawei
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Teachers' Competence and Readiness in Eco-Green Mathematics and Environmental Sustainability Literacy: An Empirical Study in Digital-AI-Based Learning [PDF]

BIO Web of Conferences
This study investigates mathematics teachers' competencies and readiness in integrating Eco-Green Mathematics, sustainability literacy, and digital-AI-based learning.
Sunismi Sunismi, Fathani Abdul Halim, Setiawan Yayan Eryk   +2 more
doaj   +1 more source