Results 61 to 70 of about 3,167,444 (296)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Artificial intelligence and informatics in sustainable marketing: Enhancing green consumer engagement [PDF]

International Journal of Data and Network Science
Marketing has shifted from transactional promotion to value-oriented engagement, where sustainability and environmental responsibility increasingly influence consumer decision-making; Artificial Intelligence (AI)-driven sustainable marketing ...
Mohammad Zulfeequar Alam, Tameem Ahmad, Md Shabbir Alam, Zainab Fatima   +3 more
doaj   +1 more source

Green Edge AI: A Contemporary Survey

Proceedings of the IEEE
30 pages, 8 figures, 5 tables, accepted to the Proceedings of the ...
Yuyi Mao, Xianghao Yu, Kaibin Huang, Ying-Jun Angela Zhang, Jun Zhang   +4 more
openaire   +5 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Towards Green AI: Current Status and Future Research

The immense technological progress in artificial intelligence research and applications is increasingly drawing attention to the environmental sustainability of such systems, a field that has been termed "Green AI".
Clemm, Christian, Wimalawarne, Kishan A.D.N.K., Stobbe, Lutz, Druschke, Jan   +3 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Evaluating the impact of artificial intelligence development on industrial green transformation in China

Scientific Reports
Amid the booming development of artificial intelligence (AI) and vigorous green transformation, the influence of AI development on industrial green transformation and its mechanisms requires scientific attention.
Weiping Zeng, Zihui Yin
doaj   +1 more source

AI-Enabled Green Hospitality Services and Customer Loyalty: The Sequential Mediating Roles of Service Quality and Green Trust

Tourism and Hospitality
Despite the growing adoption of AI-enabled green hospitality services, limited research has examined how these services influence customer loyalty through the sequential mediating roles of service quality and green trust.
Wagih Mohamed Salama
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Study of Business Practices of MSMEs applying ‘Green AI’ to Achieve ‘Sustainability’ with Special Reference to Sangli District

Journal of Asia Entrepreneurship and Sustainability
This research investigates the transformative role of "Green AI" as a strategic driver for the United Nations Sustainable Development Goals (SDGs) within the Micro, Small, and Medium Enterprise (MSME) sector.
Ms. Shilpa S. Shah, Dr. Vilas Balgaonkar
doaj   +1 more source