Results 101 to 110 of about 137,997 (282)

Green and sustainable evaluation of methods for sample treatment in drug analysis

open access: yes
The time-consuming nature of many sample treatment protocols continues to be recognized as the main bottleneck of analytical procedures, which, in most cases, use long analysis times, excessive amounts of solvents and reagents, and energy.
Martínez-Pérez-Cejuela, Héctor   +4 more
core   +1 more source

Evaluating the Greenness of Wine Analytical Chemistry: A New Metric Approach

open access: yesFoods
While the wine industry has already adopted some sustainable and environmentally friendly practices, special attention should be paid to the greenness of the analytical methodologies used. In this study, a new tool called “Green Wine Analytical Procedure
Vasiliki Thanasi   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Teaching Green Analytical Chemistry on the Example of Bioindication and Biomonitoring (B & B) Technologies

open access: yes, 2019
Teaching of Green Analytical Chemistry (GAC) requires a not inconsiderable willingness on the part of the lecturer to familiarize himself with a relatively new field in analytical chemistry.
Piotr Szefer   +62 more
core   +1 more source

Active learning oriented to green chemistry with virtual laboratories to promote higher order thinking skills to achieve quantitative analytical chemistry competency

open access: yesChemistry Teacher International
Achievement of analytical chemistry competency needs to be optimized through the application of active learning models. This research aims to design an active learning model oriented towards green chemistry with virtual laboratories to promote higher ...
Situmorang Manihar   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Green analytical chemistry – the use of surfactants as a replacement of organic solvents in spectroscopy

open access: yes, 2017
This chapter gives an introduction to the many practical uses of surfactants in analytical chemistry in replacing organic solvents to achieve greener chemistry.
Daniel Y. Pharr
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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