Results 101 to 110 of about 570,023 (290)

Chemical degradation of platinum oncolytics in urine and speciation of the inorganic contaminants cisplatin and carboplatin relevant in waste water

open access: yesEmerging Contaminants
Understanding the prevalent form of platinum (Pt) based antineoplastic agents, used in chemotherapy, is of importance to develop a remediation strategy that restricts aquatic exposure. The speciation of Pt-based compounds was measured in actual patients’
Karel Folens   +3 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Environmentally sustainable white, green and blue analytical method for simultaneous determination of ciprofloxacin and hydrocortisone using MVAS approach

open access: yesDiscover Chemistry
This study outlines the development of an environmentally sustainable green, white and blue analytical method for the simultaneous determination of Ciprofloxacin and Hydrocortisone in eardrop using the absorption ratio i.e. Q-analysis method, adhering to
Kondreddy Vinod Kumar   +2 more
doaj   +1 more source

Greenness metrics for analytical methodologies linked to mass spectrometry

open access: yesGreen Analytical Chemistry
With a global focus on sustainability and environmental impact, scientists have been prompted to adopt eco-friendly practices. Green analytical chemistry (GAC) promotes energy-efficient equipment, reduction of toxic chemicals, and sustainable waste ...
Marina Jurisch   +7 more
doaj   +1 more source

The examination of baseline noise and the impact on the interpretation of low-template DNA samples [PDF]

open access: yes, 2016
It is common practice for DNA STR profiles to be analyzed using an analytical threshold (AT), but as more low template DNA (LT-DNA) samples are tested it has become evident that these thresholds do not adequately separate signal from noise.
Wellner, Genevieve A.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Citric acid crosslinked carboxymethyl cellulose/graphene oxide bead for adsorption of tetracycline from an aqueous system

open access: yesJournal of Taibah University for Science
Tetracycline (TC) and its derivatives are emerging contaminants in water systems with potential to accumulate in living organisms and spread antibiotic resistance.
Ismaila Olalekan Saheed   +6 more
doaj   +1 more source

Green strategies in analytical chemistry

open access: yes, 2014
Sonamukhi Girls High School, Bankura, West Bengal, India Department of Chemistry, University of Burdwan, Burdwan-713 104, West Bengal, India E-mail : arabindakdas@rediffmail.com Manuscript received 06 August 2013, accepted 07 August 2013 The literature on the green strategies in analytical chemistry is comprehensively reviewed. The bottleneck of almost
Suparna Dutta, Das, Arabinda K.
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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