Results 81 to 90 of about 5,647,687 (283)
, 2018 Diabetes mellitus (DM) is considered a public health problem. The initial treatment consists of improving the lifestyle and making changes in the diet. When these changes are not enough, the use of medication becomes necessary.
Salgado, Hérida Regina Nunes [UNESP] +2 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Metrics for green analytical chemistry
Analytical Methods, 2016 Green analytical chemistry although is not a new concept, it does not have greenness metrics system. Some efforts have been made to develop suitable metrics for analytical chemistry. The present review analyses the different methods proposed for an accurate greenness metrics system.
openaire +2 more sources
Portable microwave assisted extraction: An original concept for green analytical chemistry.
, 2013 International audienceThis paper describes a portable microwave assisted extraction apparatus (PMAE) for extraction of bioac-tive compounds especially essential oils and aromas directly in a crop or in a forest.
Petitcolas, Emmanuel +3 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
European analytical column No. 36 (January 2008)
, 2008 The annual European Analytical Column informs the members of the European Association for Chemical and Molecular Sciences as well as the readers of prestigious international journals on analytical chemistry about current developments of this scientific ...
ANDERSON J.E.T. +10 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Environmental Analytical Chemistry
Environmental analytical chemistry has evolved into a well-established interdisciplinary field (analytical chemistry, pollution chemistry, chemical engineering, etc [...
Stefan Tsakovski, Tony Venelinov
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source