The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain. [PDF]
, 2016 GPIHBP1 is a glycolipid-anchored membrane protein of capillary endothelial cells that binds lipoprotein lipase (LPL) within the interstitial space and shuttles it to the capillary lumen.
Beigneux, Anne P +9 more
core +4 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Spectroscopic Evidence of Nanodomains in THF/RTIL Mixtures: Spectroelectrochemical and Voltammetric Study of Nickel Porphyrins [PDF]
, 2015 The presence and effect of RTIL nanodomains in molecular solvent/RTIL mixture were investigated by studying the spectroelectrochemistry and voltammetry of nickel octaethylporphyrin (Ni(OEP)) and nickel octaethylporphinone (Ni(OEPone)).
Atifi, Abderrahman, Ryan, Michael D.
core +1 more source
Accurate rate coefficients for models of interstellar gas-grain chemistry
, 2009 The methodology for modeling grain-surface chemistry has been greatly improved by taking into account the grain size and fluctuation effects. However, the reaction rate coefficients currently used in all practical models of gas-grain chemistry are ...
Barzel +25 more
core +1 more source
Image analysis procedure for studying Back-Diffusion phenomena from low-permeability layers in laboratory tests [PDF]
, 2016 In this study, the long-term tailing derived from the storage process of contaminants in low-permeability zones is investigated. The release from these areas in the groundwater can be considered a long-term source that often undermines remediation ...
PETRANGELI PAPINI, Marco +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
, 2019 Kinetic isotope effect (KIE) is a common physicochemical effect to elucidate complicated microscopic reaction mechanism in biological, chemical and physical systems.
Sakaushi, Ken
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Effective destruction of CO by cosmic rays: implications for tracing H$_2$ gas in the Universe [PDF]
, 2015 We report on the effects of cosmic rays (CRs) on the abundance of CO in $\rm H_2$ clouds under conditions typical for star-forming galaxies in the Universe. We discover that this most important molecule for tracing H$_2$ gas is very effectively destroyed
Bisbas, Thomas G. +2 more
core +2 more sources
FTIR-DRIFTS-based prediction of β-carotene, α-tocopherol and L-ascorbic acid in mango (Mangifera indica L.) fruit pulp [PDF]
, 2020 Mango fruits contain substantial vitamins and dietary fibre. Vitamins vary among and within fruits depending on cultivar type and ripening stage. Conventional techniques of vitamins analysis are based on High Pressure Liquid Chromatography, which are ...
Mohammed, Salim Ali +4 more
core +1 more source