Results 71 to 80 of about 134,169 (249)

Chemical degradation of platinum oncolytics in urine and speciation of the inorganic contaminants cisplatin and carboplatin relevant in waste water

Emerging Contaminants
Understanding the prevalent form of platinum (Pt) based antineoplastic agents, used in chemotherapy, is of importance to develop a remediation strategy that restricts aquatic exposure. The speciation of Pt-based compounds was measured in actual patients’
Karel Folens, Janis Baeten, Karen Couvreur, Gijs Du Laing   +3 more
doaj   +1 more source

Combining Normal/Reversed-Phase HPTLC with Univariate Calibration for the Piperine Quantification with Traditional and Ultrasound-Assisted Extracts of Various Food Spices of Piper nigrum L. under Green Analytical Chemistry Viewpoint. [PDF]

Molecules, 2021
Alqarni MH, Alam P, Foudah AI, Muharram MM, Shakeel F.   +4 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Principles of green chemistry: building a sustainable future

Discover Chemistry
Green chemistry is an interdisciplinary field that focuses on minimizing hazardous substances and promoting sustainable alternatives in chemical processes to conventional chemical processes and products.
Fatma Kurul, Beyzanur Doruk, Seda Nur Topkaya   +2 more
doaj   +1 more source

Greenness metrics for analytical methodologies linked to mass spectrometry

Green Analytical Chemistry
With a global focus on sustainability and environmental impact, scientists have been prompted to adopt eco-friendly practices. Green analytical chemistry (GAC) promotes energy-efficient equipment, reduction of toxic chemicals, and sustainable waste ...
Marina Jurisch, Júlia Célia Lima Gomes, Brícia Marques Parreiras, João Victor Coelho Pimenta, Túlio Miranda Sepulveda, Adriana Nori de Macedo, Brenda Lee Simas Porto, Rodinei Augusti   +7 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Unveiling advanced green assessment of simple and cost effective spectrophotometric determination of domperidone and pantoprazole for gastrointestinal disorders

Scientific Reports
In the pursuit of sustainable pharmaceutical analysis, Green Analytical Chemistry emerges as a vital approach to protect both human health and the environment.
Eman Darweish, Magda Mohamed El-Henawee, Mona Abd Elnasser Labib, Naglaa Abdel Sattar Kabil   +3 more
doaj   +1 more source

Citric acid crosslinked carboxymethyl cellulose/graphene oxide bead for adsorption of tetracycline from an aqueous system

Journal of Taibah University for Science
Tetracycline (TC) and its derivatives are emerging contaminants in water systems with potential to accumulate in living organisms and spread antibiotic resistance.
Ismaila Olalekan Saheed, Bashir Pelumi Raji, Maryam Nike Abdul-Raheem, Samsudeen Olanrewaju Azeez, Akeem Adebayo Jimoh, Megat Ahmad Kamal Megat Hanafiah, Faiz Bukhari Mohd Suah   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source