Results 91 to 100 of about 8,592,856 (257)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

GResilient index to assess the greenness and resilience of the automotive supply chain [PDF]

Purpose: The purpose of this paper is to suggest an Index entitled GResilient Index to assess the greenness and resilience of the automotive companies and corresponding supply chain. Design/methodology/approach: An integrated assessment model is proposed
Carvalho, Helena, Govindan, Kannan, Azevedo, Susana G., Cruz-Machado, V.   +3 more
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Sustainable RP-HPLC method for rapid quantification of arformoterol: development, validation, and greenness assessment

Discover Materials
Objective The current research work aimed to establish a sustainable and eco-friendly RP-HPLC method for the separation and estimation of Arformoterol in bulk and dosage forms.
Ramreddy Godela, Krishnaphanisri Ponnekanti, Santhoshi Priya Dandamudi, Dasari Durga Bhavani, Gargula Sumana, Karnati Shiva Reddy   +5 more
doaj   +1 more source

Sustainability assessment in food analysis: the application of Green Analytical Chemistry tools to phthalate residue analysis in edible oils

Exploration of Foods and Foodomics
Edible oils are essential in daily diet due to their high contribution of fatty acids, fat-soluble vitamins, and triglycerides. During the processes of growing, processing, storage, transport, or packaging, they can be contaminated by ubiquitous ...
Daniel Gallart-Mateu
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Greenness appraisal and development of validated spectrophotometric methods for assay of amprolium: Comparative study using Analytical Eco-Scale, GAPI, and AGREEmetric approaches

Green Analytical Chemistry
Intestinal coccidiosis is a serious parasitic disease in poultry. Amprolium hydrochloride(AMP) is widely used for the treatment and prevention of coccidiosis.
Nehal W. El-Sayed, Rasha M. Youssef, Samir Morshedy, Miranda F. Kamal   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A comparative evaluation of analytical green metrics for microextraction techniques based on polymeric and gel membranes as solid support

Sample preparation plays a pivotal role in chemical analysis, serving to isolate target analytes from diverse matrices and enhance measurement selectivity and sensitivity. This review examines microextraction's eco-friendliness versus tradition, focusing
Dorabadizare, Farzaneh, Sedehi, Samira, Pedersen-Bjergaard, Stig, Ramos Payán, María Dolores, Tabani, Hadi   +4 more
core   +1 more source

A dual-index based analytical approach for DG planning considering power losses [PDF]

, 2012
This paper presents a new multiobjective index-based analytical methodology to calculate the optimal size and power factor of distributed generation (DG) unit at various locations.
Duong Quoc Hung, Mithulananthan, N., N. Mithulananthan, N. Mithulananthan, Lomi, A., Lomi, Abraham, Hung, Duong Quoc   +5 more
core