Results 71 to 80 of about 8,592,856 (257)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Trio-colored appraisal of an eco-conscious method for the determination of bisphenol A in drinking water bottles and pharmaceutical eye-drop solutions

BMC Chemistry
Bisphenol A (BPA) is a hazardous endocrine-disrupting compound which is frequently detected in water sources due to its extensive application in plastic manufacturing.
Farah S. Elbitar, Lobna A. Hussein, Noha M. El Zahar, Hend Z. Yamani, Fotouh R. Mansour   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Prospect Green Map: a community map of environmental, historical, cultural, civic, and recreational sites

A map detailing the sites of interest and importance in the Prospect, NC, and the Robeson County area of North Carolina.
Robeson County Green Map Project
core   +1 more source

Application of recycled battery graphite decorated with poly hippuric acid/ multiwalled carbon nanotubes as an ecofriendly sensor for serotonin

Scientific Reports
A novel modified sensor based on electropolymerization of hippuric acid (HA) using cyclic voltammetry within the potential window − 1 to 1.5 V for 10 cycles at a scan rate 100 mV s−1 over multiwalled carbon nanotubes (MWCNTs) on battery graphite ...
Aya G. Abd El-Nasser, Mahmoud G. Metwally, Azza A. Shoukry, Rasha M. El Nashar   +3 more
doaj   +1 more source

Portable microwave assisted extraction: An original concept for green analytical chemistry.

, 2013
International audienceThis paper describes a portable microwave assisted extraction apparatus (PMAE) for extraction of bioac-tive compounds especially essential oils and aromas directly in a crop or in a forest.
Petitcolas, Emmanuel, de La Guardia, Miguel, Perino, Sandrine, Chemat, Farid   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Eco-Friendly Capillary Electrophoresis Method for the Quantification of Apixaban in Oral Dosage Form

Separations
The present work describes, for the first time, an eco-friendly capillary zone electrophoresis (CZE) methodology for determining apixaban (APX), an oral anticoagulant.
Manoelly Oliveira Rocha, Amanda Mohr, Leandro Kolling, Marcia Messias da Silva, Jacqueline Arguello da Silva, Martin Steppe   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source