Results 61 to 70 of about 8,592,856 (257)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Greenness and whiteness appraisal for bioanalysis of quetiapine, levodopa and carbidopa in spiked human plasma by high performance thin layer chromatography

open access: yesBMC Chemistry
A sustainable HPTLC-densitometric method was developed for quantitative determination of Quetiapine (QUET), Levodopa (LD) and Carbidopa (CD) in presence of Dopamine (DOP) as an internal standard.
Finan T. Hindam   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Price Volatility and Banking in Green Certificate Markets [PDF]

open access: yes
There is concern that prices in a market for Green Certificates (GCs) primarily based on volatile wind power will fluctuate excessively, leading to corresponding volatility of electricity prices.
Eirik S. Amundsen   +2 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From design space to green space: an analytical quality by design–assisted high-performance liquid chromatography method for the quantification of triple-combination antihypertensive drugs

open access: yesBMC Chemistry
To develop a reliable, High-performance Liquid Chromatography technique for the simultaneous determination of a Fixed-Dose Combination of hydrochlorothiazide, amlodipine besylate, and telmisartan. The concepts of Green Analytical Chemistry and Analytical
Suvarna Yenduri   +2 more
doaj   +1 more source

Green methods for determination of paracetamol in drug samples: A comparative study

open access: yesGreen Analytical Chemistry
Non-steroidal anti-inflammatory drugs like paracetamol, which have strong antibacterial and analgesic properties, are frequently employed in medicine.
Elham N. Mezaal   +5 more
doaj   +1 more source

Green Analytical Chemistry: A Comprehensive Review of Eco-Scale, Greenness Metrics, and Sustainability Approaches [PDF]

open access: yes
Green analytical chemistry (GAC) is developing quickly at the moment, necessitating the establishment of clear, succinct guidance in the form of GAC principles that will aid in greening laboratory operations.
Afreen, Dr   +2 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Assessing environmental sustainability of HPLC methods for tri-combination anti-hypertensive drug analysis

open access: yesGreen Analytical Chemistry
Ecological issues are raised by analytical research methods that harm the environment, such as liberating dangerous solvents into the atmosphere. Sustainable analytical techniques should consider method performance, eco-friendliness, productivity, and ...
Naga Prashant K   +2 more
doaj   +1 more source

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