Results 91 to 100 of about 307,504 (304)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Communications ChemistryThe use of weak, inexpensive bases in the assembly of late-transition metal NHC complexes represents a most promising synthetic strategy. We now disclose the use of gaseous and aqueous ammonia as bases for the continuous-flow synthesis of these complexes
Riku Saito +4 more
doaj +1 more source
Intensified processes for FAME production from waste cooking oil: a technological review [PDF]
, 2013 This article reviews the intensification of fatty acid methyl esters (FAME) production from waste cooking oil (WCO) using innovative process equipment. In particular, it addresses the intensification of WCO feedstock transformation by transesterification,
Aubin, Joelle +2 more
core +4 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Sustainable Management of Metals: An Analysis of Global Research [PDF]
, 2018 The objective of this study was to analyze research trends in the field of sustainable management of metals on a global level between 1993 and 2017. To do so, a bibliometric analysis was carried out on a total of 6967 articles.
Aznar Sánchez, José Ángel +3 more
core +1 more source
Decision-making model on sustainable supply chain finance under uncertainties [PDF]
, 2018 Supply chain finance has received increasing attention. The combination of sustainable development and supply chain finance requires a deeper discussion to address the theoretical and managerial gaps. Thus, this study adopts the fuzzy Technique for Order
Hu, Jiayao +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Life cycle assessment (LCA) applied to the process industry: a review [PDF]
, 2011 Purpose : Life cycle assessment (LCA) methodology is a well-established analytical method to quantify environmental impacts, which has been mainly applied to products. However, recent literature would suggest that it has also the potential as an analysis
Jacquemin, Leslie +2 more
core +6 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source