Results 81 to 90 of about 58,468 (260)
Advances in green chemistry and engineering
Green chemistry and engineering seek for maximizing efficiency and minimizing negative impacts on the environment and human health in chemical production processes.
Jechan Lee, Assunta Marrocchi
doaj +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Resource use efficiency has become increasingly important as the global demand for natural resources continues to grow, necessitating innovative and sustainable utilization strategies.
Maria Ignacia Rodriguez Escobar +5 more
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Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Eucalyptus lignin production coupled with Cellic ® CTec3 HS enzymatic hydrolysis to monosaccharides
The aim of this work was to design, develop, and optimise a two-step process for extracting lignin from Eucalyptus globulus residues and subsequently converting the remaining holocellulose into monosaccharides, primarily glucose and xylose.
Antonio Caporusso +5 more
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Lignocellulosic biomass is currently widely used in many biorefining processes. The full exploitation of biomass from uncultivated or even marginal lands for the production of biobased chemicals has deserved huge attention in the last few years.
Vittoria Fatta +9 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
This article introduces the concept of green chemical engineering as the intersection of “green chemistry” and “green engineering”, emphasizing its importance in the chemical engineering curriculum.
E. Vashghani-Farahani, S. Rafiyan
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