Results 51 to 60 of about 379,363 (258)

Pseudo-Static Design and Analysis of Seismic Earth Pressure for Cantilever Retaining Walls with Limitation Assessment

Designs
By critically reviewing pseudo-static methods, it is demonstrated that approximating the earth pressure on a short heel’s vertical face (V-plane) using the Rankine solution for long-heel walls induces a negligible error.
Zhiliang Sun, Wei Wang, Hanghang Liu
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Comparison Study of Novel Flat Evaporator Loop Heat Pipes with Different Types of Condensation Pipeline

Energies
Chip-level cooling has become a thermal bottleneck in next-generation data centers. Although previous studies have optimized evaporator wick structures, they are limited to a single condensation path and ignore the combined effects of the loop heat pipe (
Kangning Xiong, Yang Liu, Zhuoyu Li, Qingsong Pan   +3 more
doaj   +1 more source

Building Geometry Simplification for Improving Mesh Quality of Numerical Analysis Model

Applied Sciences, 2020
Numerical analysis, especially the finite volume method (FVM), is one of the primary approaches employed when evaluating a building environment. A complicated geometry can degrade the mesh quality, leading to numerical diffusions and errors.
Gwanyong Park, Changmin Kim, Minhyung Lee, Changho Choi   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

New model and practice of zero-carbon solar district heating in Xizang Plateau

Xi'an Gongcheng Daxue xuebao
The Xizang Plateau has a long and cold winter, and the reserves of conventional energy such as coal and natural gas are nearly zero, making building heating a great challenge.
LIU Jiaping, WANG Dengjia, JIAO Qingtai, LIU Yanfeng, QU Lei   +4 more
doaj   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source