Results 61 to 70 of about 2,546,109 (292)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Building Geometry Simplification for Improving Mesh Quality of Numerical Analysis Model

Applied Sciences, 2020
Numerical analysis, especially the finite volume method (FVM), is one of the primary approaches employed when evaluating a building environment. A complicated geometry can degrade the mesh quality, leading to numerical diffusions and errors.
Gwanyong Park, Changmin Kim, Minhyung Lee, Changho Choi   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Kajian Green Building Pada Gedung Dekanat Fakultas Teknik Universitas Brawijaya Malang [PDF]

, 2016
Green Building merupakan suatu konsep bangunan ramah lingkungan yang sudah menjadi perhatian khususnya di negara beriklim tropis. Indonesia merupakan negara dengan iklim tropis dengan suhu dan kelembaban yang tinggi.
Adhitama, M. S. (Muhammad), Dewa, B. P. (Barra), Nugroho, A. M. (Agung)   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Penilaian Kriteria Green Building Pada Gedung Teknik Sipil ITS [PDF]

, 2012
Green building merupakan suatu konsep bangunan ramah lingkungan yang sudah menjadi perhatian khusus di berbagai negara dan mulai diterapkan di Indonesia. Konsep Green Building merupakan salah satu upaya penghematan energi yang dapat diterapkan pada suatu
Putri, A. A. (Aristia), Rohman, M. A. (M), Utomo, C. (Christiono)   +2 more
core   +3 more sources

Comparison Study of Novel Flat Evaporator Loop Heat Pipes with Different Types of Condensation Pipeline

Energies
Chip-level cooling has become a thermal bottleneck in next-generation data centers. Although previous studies have optimized evaporator wick structures, they are limited to a single condensation path and ignore the combined effects of the loop heat pipe (
Kangning Xiong, Yang Liu, Zhuoyu Li, Qingsong Pan   +3 more
doaj   +1 more source

Aplikasi Green Building pada Kantor AMG Tower Surabaya [PDF]

, 2017
Saat ini konsep bangunan ramah lingkungan menjadi isu yang banyak dikaji di Indonesia. Kantor AMG Tower dipilih sebagai objek penelitian karena berdiri pada lahan yang disediakan untuk area komersial, berlantai banyak karena memiliki 23 lantai, memiliki ...
Afrandi, I. (Irfan), Putranto, A. D. (Ary)   +1 more
core  

A Review of Green Building Development in China from the Perspective of Energy Saving [PDF]

, 2018
This paper reviews the history of green building development and assessment standards in China, particularly from the perspective of energy saving. It is divided into four parts: (1) the development of policies of green building in China that have been ...
Jin, H, Kang, J, Zhang, Y
core   +2 more sources