Results 91 to 100 of about 827,595 (342)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Due to increase in growth of real estate development, green certification systems are essential to ensure the well-being of society and environment. Green Building Councils are the main drivers that influence many factors related to development of green ...
Mishra Ankit, Kauškale Linda
doaj +1 more source
A barrier to green-building development is the uncertainty and scepticism about the financial implications. This study aimed to investigate whether the green-certification schemes help buyers to recognize the benefits of green office buildings by their ...
Jayantha Wadu Mesthrige, Hoi-Ting Chan
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Environmental pollutants including ultrafine particulate matter (UFPs) and adverse meteorological conditions pose significant public health impacts, particularly affecting respiratory health.
Ziyu Shu +7 more
doaj +1 more source
Sustainability of Sustainable Real Property Development [PDF]
The paper investigates commercial buildings users' perception of the benefits of green buildings and how this perception influences their decision to occupy and/or invest in them.
Addae-Dapaah, K +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Rebuilding Our Way to a Sustainable Recovery: Making Commercial Building Retrofit Jobs into Quality Jobs for Our Communities [PDF]
This paper provides some background on the opportunities created by widespread retrofitting in the Commercial Real Estate (CRE) industry and the innovative policies that municipalities have implemented to give building owners incentives to upgrade their ...
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