Results 71 to 80 of about 1,652,756 (337)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Guided by the principles of environmental sustainability, and drawing on extant literature that highlight the limited integration of green chemistry in secondary science education, this study examined the influence of gender on chemistry teachers ...
David Adeyemi Aladesuyi +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Keanekaragaman hayati Indonesia dapat dijadikan sebagai sumber belajar dan dikembangkan menjadi bahan ajar bagi peserta didik. Melalui penelitian ini, akan dikembangkan bahan ajar berupa Lembar Kegiatan Peserta Didik (LKPD) berdasarkan sumber belajar ...
Orin Uniati +2 more
doaj +1 more source
Green chemistry and biorefineries: common future? [PDF]
Green Chemistry and Biorefinery concepts are two approaches helping to develop new and more sustainable processes.The implementation of both methodologies impels to fossil-independent future with bioeconomy based on natural feedstock like biowaste and ...
Carvalho, V. +7 more
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The chemistry of Pseudocyphellaria impressa S. Lat. in New Zealand [PDF]
As part of a detailed study of the nomenclature and taxonomy of the New Zealand species of Pseudocyphellaria it has been noted that the chemistry of the P. impressa (Hook & Taylor) Vainio aggregate, that is species with a markedly faveolate (honeycomb-
James, P.W., Wilkins, Alistair L.
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Dos primeiros aos segundos doze princípios da Química Verde
The second 12 principles of Green Chemistry (Winterton, 2001) are presented and discussed to show how they press academic chemists to focus the invention of synthetic pathways more directly on industrial process development, allowing a quicker progress ...
Adélio A. S. C. Machado
doaj +1 more source

