Results 71 to 80 of about 265,138 (260)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Green Chemistry and Technology for Sustainable Development

International Journal of Scientific Research in Science and Technology
Green chemistry is one of the most explored topics these days. Major research on green chemistry aims to reduce or eradicate the production of harmful bi-products and maximizing the desired product in an eco-friendly way. Green chemistry is required to minimize the harm of nature by anthropogenic materials and the processes applied to generate them ...
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

ACCELERATING GREEN CHEMISTRY WITH AI TECHNOLOGIES

In recent years, the intersection of artificial intelligence (AI) and chemistry has sparked a profound transformation in molecular science. As we stand on the brink of a new era in scientific discovery, the application of AI technologies promises to revolutionize the way we understand, analyze, and manipulate chemical systems.
Agnihotri, Laxmi, Tiwari, Kanha Singh
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Metallaphotoredox-catalyzed alkynylcarboxylation of alkenes with CO2 and alkynes for expedient access to β-alkynyl acids

Nature Communications
Carboxylation with CO2 offers an attractive and sustainable access to valuable carboxylic acids. Among these methods, direct C−H carboxylation of terminal alkynes with CO2 has attracted much attention for one-carbon homologation of alkynes, enabling ...
Jin-Cheng Xu, Jun-Ping Yue, Min Pan, Yi-Chi Chen, Wei Wang, Xi Zhou, Wei Zhang, Jian-Heng Ye, Da-Gang Yu   +8 more
doaj   +1 more source

Polylactides—Chemistry, Properties and Green Packaging Technology: A Review

International Journal of Food Properties, 2011
Polylactide (PLA), a biodegradable aliphatic polyester, has been studied extensively for its wide applications in various fields from food packaging to interior materials for automobiles. One of PLA's advantages is that the raw material, lactic acid can be derived from renewable resources, which makes PLA very attractive for the packaging and ...
Jasim Ahmed, Sunil K. Varshney
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Research Progress of Mechanoenzyme Catalysis and Its Application in Food Field

Shipin gongye ke-ji
Mechanoenzyme catalysis is an emerging biocatalysis technology. This technology can significantly improve the reaction efficiency, reduce the use of solvents and enhance the stability of enzymes by mechanochemical means to strengthen the enzyme-catalyzed
Mengdi ZHENG, Jiaying XIN, Tianyu CUI, Lixin CHEN, Wei CHENG, Tianfu LIU   +5 more
doaj   +1 more source