Results 121 to 130 of about 8,706,014 (300)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2003 A map of the Asagaya station in Tokyo and its surrounding area. The map highlights places of interest for sustainable living, nature, culture and society. It was created by children around the concept, ‘town where human and nature live together’, as part
Sense of Wonder
core +1 more source
Scattering Properties of Impulsive Discrete Dirac System with Hyperbolic Eigenparameter
Journal of Mathematical Sciences and ModellingIn this work, we examine the spectral and scattering properties of an impulsive discrete Dirac system with hyperbolic parameter such as resolvent operator, the set of eigenvalues, Jost function, scattering solutions and scattering function.
Güler Başak Öznur
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
MathematicsIn this paper, we investigate a class of nonlinear fractional boundary value problems involving the Caputo fractional derivative under two-point boundary conditions.
Nadiyah Hussain Alharthi +2 more
doaj +1 more source
ON POSITIVE GREEN'S FUNCTIONS [PDF]
Proceedings of the National Academy of Sciences, 1954 openaire +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On the Expansion of Green's Function [PDF]
Proceedings of the National Academy of Sciences, 1935 openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source