Results 141 to 150 of about 4,955,537 (296)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Nonlinear Fractional Boundary Value Problems: Lyapunov-Type Estimates Derived from a Generalized Gronwall Inequality

open access: yesMathematics
In this paper, we investigate a class of nonlinear fractional boundary value problems involving the Caputo fractional derivative under two-point boundary conditions.
Nadiyah Hussain Alharthi   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A problem with the operator M. Saigo in the boundary condition for a loaded heat conduction equation

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2012
The existence of a unique solution of the non-classical boundary value problem for the heat equation, the loaded value of the desired function $u(x, y)$ on the boundary $x = 0$ of the rectangular area $\Omega= \{ (x, t) : 0$ < $x$ < $l$, $0$ < $t$ < $T \}
Anna V Tarasenko
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Monte-Carlo estimations for powers of Green operator and the first eigenvalue for Dirichlet boundary value problem

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
In this paper, we examine the algorithm for computing the powers of a Green operator and the first eigenvalue for the Dirichlet boundary value problem using Monte-Carlo method. The efficiency of numerical realization of these algorithms is also discussed.
Andrey N Kuznetsov   +2 more
doaj  

ON POSITIVE GREEN'S FUNCTIONS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1954
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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