Results 131 to 140 of about 8,706,014 (300)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Green function of correlated genes in a minimal mechanical model of protein evolution. [PDF]

open access: yesProc Natl Acad Sci U S A, 2018
Dutta S   +3 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Policies for a green transition: Exploring contemporary environmental and sustainability policies for green guidance [PDF]

open access: yes
This paper explores the current international landscape for environmental and sustainability policies. It finds a strong consensus exists around the need to address climate change, with many countries utilising the UN’s Sustainable Development Goals to ...
Wrzosek, M.   +7 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Green family collection

open access: yes
This collection contains correspondence and other information on the Green family, which settled in and around what is now northern Lonoke County before the Civil ...
Green family
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A problem with the operator M. Saigo in the boundary condition for a loaded heat conduction equation

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2012
The existence of a unique solution of the non-classical boundary value problem for the heat equation, the loaded value of the desired function $u(x, y)$ on the boundary $x = 0$ of the rectangular area $\Omega= \{ (x, t) : 0$ < $x$ < $l$, $0$ < $t$ < $T \}
Anna V Tarasenko
doaj  

Home - About - Disclaimer - Privacy