Results 61 to 70 of about 13,472,146 (356)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Existence Results for Some p-Laplacian Langevin Problems with a ψ-Hilfer Fractional Derivative with Antiperiodic Boundary Conditions

Fractal and Fractional
In this work, we establish the existence of at least one solution for a p-Laplacian Langevin differential equation involving the ψ-Hilfer fractional derivative with antiperiodic boundary conditions. More precisely, we transform the studied problem into a
Lamya Almaghamsi, Samah Horrigue
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Existence and stability of a positive solution for nonlinear hybrid fractional differential equations with singularity

Journal of Taibah University for Science, 2019
In this paper, we will study solution existence and its stability for hybrid fractional DE with fractional integral, fractional differential derivative and Φp-operator in Caputo sense.
Wadhah Al-Sadi, Huang Zhenyou, Abdulwasea Alkhazzan   +2 more
doaj   +1 more source

On a Riemann–Liouville Type Implicit Coupled System via Generalized Boundary Conditions

Mathematics, 2021
We study a coupled system of implicit differential equations with fractional-order differential boundary conditions and the Riemann–Liouville derivative.
Usman Riaz, Akbar Zada, Zeeshan Ali, Ioan-Lucian Popa, Shahram Rezapour, Sina Etemad   +5 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Continuum Limit of the Green Function in Scaled Affine ${\phi }_4^4$ Quantum Euclidean Covariant Relativistic Field Theory

Quantum Reports
Through path integral Monte Carlo computer experiments, we prove that the affine quantization of the φ44-scaled Euclidean covariant relativistic scalar field theory is a valid quantum field theory with a well-defined continuum limit of the one- and two ...
Riccardo Fantoni
doaj   +1 more source

Fundamental solution of thermal stress field in porous infinite media subjected to gas infiltration and heat transfer

Nihon Kikai Gakkai ronbunshu, 2014
When a porous solid is subjected to both gas infiltration and heat transfer, thermal stresses are generated in such a solid. In the previous reports, fundamental theory for a porous solid under such a complex situation was developed, and then a thermal ...
Masayuki ARAI
doaj   +1 more source

Some results on fractional Hahn difference boundary value problems

Demonstratio Mathematica, 2023
Fractional Hahn boundary value problems are significant tools to describe mathematical and physical phenomena depending on non-differentiable functions.
Baheeg Elsaddam A., Oraby Karima M., Akel Mohamed S.   +2 more
doaj   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source