Results 71 to 80 of about 164,144 (293)

Biochar Amendment as a Mitigation Against Freezing–Thawing Effects on Soil Hydraulic Properties

open access: yesAgronomy
Seasonal freeze–thaw cycles compromise soil structure, thereby increasing hydraulic conductivity but diminishing water retention capacity—both of which are essential for sustaining crop health and nutrient retention in agricultural soils.
Zhongkui Chen   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Assessment of Green Infrastructure for Conservation Planning using Cadastral Data in Seoul, South Korea

open access: yesEnvironmental Science and Sustainable Development, 2018
Green infrastructure has been used for environmental conservation and management with many similar concepts such as green-space network, green-link network, and green-ways network based on the objectives of the cities for greening.
Gon Park
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Transformation towards sustainable green infrastructure systems in Egyptian villages (a case study of Fayoum villages) [PDF]

open access: yesJES: Journal of Engineering Sciences
The importance of the rural community is shaped in Egypt, where more than 57.8% of the population lives. The Egyptian village is the smallest urban environmental unit that has social, cultural and political characteristics different from the city and has
Esraa Ezzeldien   +3 more
doaj   +1 more source

The effects of urban development and current green infrastructure policy on future climate change resilience

open access: yesEcology and Society, 2020
Governments around the world are beginning to plan for the effects of climate change. In Philadelphia, Pennsylvania, USA, the city is implementing a variety of green infrastructure practices through the program Green Cities, Clean Waters to meet state ...
Charlotte Shade   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Construction of machine learning model driven by attention mechanism for AnMBR membrane fouling prediction

open access: yesGongye shui chuli
Anaerobic membrane bioreactor(AnMBR) is a very effective wastewater resource treatment process, while membrane fouling can lead to the increase of transmembrane pressure(TMP), affecting operational performance and membrane life. A machine learning model (
XIE Boxun   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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