Results 81 to 90 of about 5,951,442 (292)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Infrastructure priority list [PDF]

, 2016
The Infrastructure Priority List is a prioritised list of nationally significant investments. It provides decision makers with advice and guidance on specific infrastructure investments that will underpin Australia\u27s continued prosperity ...
Infrastructure Australia
core  

Assessment of Green Infrastructure for Conservation Planning using Cadastral Data in Seoul, South Korea

Environmental Science and Sustainable Development, 2018
Green infrastructure has been used for environmental conservation and management with many similar concepts such as green-space network, green-link network, and green-ways network based on the objectives of the cities for greening.
Gon Park
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Community Green Map Detroit

, 2003
A map of a small area of Detroit done by children, which includes descriptions and photographs of the community gathering that produced the ...
Detroit Green Map Team
core   +1 more source

Green infrastructure

4D, 2012
Within the United Kingdom, Natural England is a quasi-non-governmental organisation that has the expertise and resource to advise the government via practical, researchbased evidence on best-practice operations relating to the safeguarding of England’s ...
Nigel Thorne
doaj  

Construction of machine learning model driven by attention mechanism for AnMBR membrane fouling prediction

Gongye shui chuli
Anaerobic membrane bioreactor(AnMBR) is a very effective wastewater resource treatment process, while membrane fouling can lead to the increase of transmembrane pressure(TMP), affecting operational performance and membrane life. A machine learning model (
XIE Boxun, ZHAO Haicen, CHEN Jie, ZHANG Meng, ZHANG Xinbo   +4 more
doaj   +1 more source

Transformation towards sustainable green infrastructure systems in Egyptian villages (a case study of Fayoum villages) [PDF]

JES: Journal of Engineering Sciences
The importance of the rural community is shaped in Egypt, where more than 57.8% of the population lives. The Egyptian village is the smallest urban environmental unit that has social, cultural and political characteristics different from the city and has
Esraa Ezzeldien, Randa Gala, Ashraf Khader, Wesam Mostafa Emam   +3 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source