Results 81 to 90 of about 779,813 (264)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Study of the Inhibition Capacity of a Novel Ilex guayusa Green Extract for Preventing Corrosion in Mild Steel Exposed to Different Conditions

open access: yesAnalytica
Corrosion is a critical industrial problem. To solve this problem, the present research analyzed the influence of corrosive media on the efficiency of a guayusa inhibitor.
Juan Hidalgo   +7 more
doaj   +1 more source

The Inhibitive Effect of Vitamin-C on the Corrosive Performance of Steel in HCl Solutions

open access: yesInternational Journal of Electrochemical Science, 2013
The inhibitive behaviour of Vitamin C (ascorbic acid), as a type of green inhibitor, on the corrosive behaviour of stainless-steel (SS) X4Cr13 within an aqueous solution of hydrochloric acid (HCl) was studied within a concentration range of 0.01 - 5.0 M ...
Regina Fuchs-Godec   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Exploring Strobilanthes crispus as a Sustainable Corrosion Inhibitor for Aluminium: Electrochemical Insight Across pH Variations

open access: yesIndonesian Journal of Chemistry
Strobilanthes crispus leaf extract was investigated as a green corrosion inhibitor for aluminium in varying pH media (HCl pH 2, NaCl pH 7, NaOH pH 10). FTIR confirmed C–O and C=O functional groups are critical for inhibition.
Yasin Albarqouni   +3 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy