Results 81 to 90 of about 550,105 (304)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Detection of biological active substances and lipase inhibitors from aqueous extracts of some legumes in comparison with Orlistat drug

مجلة مركز بحوث التقنيات الاحيائية, 2014
This research was aimed to determine biological active substances qualitatively in vicia faba, lentil, green peas, soybean, beans, redbean. Lipase inhibitors were screened and compared with orlistat drug. All cold and hot extracts contained both saponin
K. A. A. Al- Khafaji, S. G. Omran, Manal Al-Latef Hasan, A. S. Salman, S. A. Rheem Mahmood   +4 more
doaj   +1 more source

An overview of green corrosion inhibitors

International Journal of Research in Engineering and Innovation
Corrosion inhibitors that are eco-friendly have become increasingly important due to growing environmental awareness and various regulations that restrict the use of conventional corrosion inhibitors because of their harmful effects. Natural products are a great source for making eco-friendly corrosion inhibitors since they contain elements such as O ...
Ekhlas Abd-Alkuder Salman, Abeer K. Shams, Khalida Abaid Samawi, Amina M. Abass, Taghried Ali Salman   +4 more
openaire   +1 more source

Advances in green hydrate inhibitors

Global Journal of Engineering and Technology Advances
Gas hydrate blockage is a major issue that the production and transportation processes in the oil/gas industry faces. The formation of gas hydrates in pipelines results in significant financial losses and serious safety risks. To tackle the flow assurance issues caused by gas hydrate formation in the pipelines, some physical methods and chemical ...
Green, Ibim-Abba, Appah, Dulu, Onyekonwu, Mike, Odutola, Toyin-Olabisi, Osokogwu, Uche   +4 more
openaire   +2 more sources

Pyrazine Derivatives as Green Corrosion Inhibitors [PDF]

, 2021
Pyrazine is a six-member heterocyclic compound containing two nitrogen atoms, located at one-fourth position. A pyrazine and its derivatives are most commonly used as a pharmaceutical, food colouring agent and as a corrosion inhibitor. It has chemistry and chemical characteristics due to nitrogen atoms present which can be obtained from both naturally ...
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Differential effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway in acute lymphoblastic leukemia

, 2013
Purpose: Aberrant PI3K/AKT/mTOR signaling has been linked to oncogenesis and therapy resistance in various malignancies including leukemias. In Philadelphia chromosome (Ph) positive leukemias, activation of PI3K by dysregulated BCR-ABL tyrosine kinase ...
Oliver G Ottmann, Martin Ruthardt, Oliver G. Ottmann, Oliver G. Ottmann (485229), Falkenburg, J.H.F., Marcus Liebermann (485228), Bart A. Nijmeijer (485227), Pfeifer, Heike, Falkenburg, J. H. Frederik, J. H. Frederik Falkenburg, Ruthardt, Martin, Tamara Tesanovic, Tesanovic, Tamara, Bart A Nijmeijer, Heike Pfeifer, Ottmann, Oliver G., Susanne Badura (485223), Sylvia Wystub, Sylvia Wystub (485226), Liebermann, M., Marcus Liebermann, Bart A. Nijmeijer, Ottmann, O.G., Nijmeijer, Bart A., Badura, S., Susanne Badura, Wystub, Sylvia, Pfeifer, H., J H Frederik Falkenburg, Tamara Tesanovic (485224), Martin Ruthardt (66634), Wystub, S., Nijmeijer, B.A., Ruthardt, M., Tesanovic, T., Badura, Susanne, Heike Pfeifer (485225), J. H. Frederik Falkenburg (210432), Liebermann, Marcus   +38 more
core   +1 more source

Experimental and theoretical investigation of mild steel corrosion control in acidic solution by Ranunculus arvensis and Glycine max extracts as novel green inhibitors. [PDF]

Heliyon, 2022
Sajadi GS, Naghizade R, Zeidabadinejad L, Golshani Z, Amiri M, Ali Hosseini SM.   +5 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source