Results 71 to 80 of about 717,872 (347)

Sigma web interface for reactor data applications [PDF]

open access: yes, 2010
We present Sigma Web interface which provides user-friendly access for online analysis and plotting of the evaluated and experimental nuclear reaction data stored in the ENDF-6 and EXFOR formats.
Pritychenko, B., Sonzogni, A. A.
core   +3 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Specific Adhesion of Membranes Simultaneously Supports Dual Heterogeneities in Lipids and Proteins [PDF]

open access: yes, 2015
Membrane adhesion is a vital component of many biological processes. Heterogeneities in lipid and protein composition are often associated with the adhesion site. These heterogeneities are thought to play functional roles in facilitating signalling. Here
Gordon, Vernita D.   +3 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Changes in Scholarly Communications and University Libraries : Electronic Journals, Open Access, Institutional Repository

open access: yes, 2005
This article describes the present situation and recent changes in scholarly communications, focusing on the Open Access and related movements and the activities and roles of university libraries in Japan.
Kimura, Masaru   +2 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

The Sound of the Crowd: Using Social Media to develop best practices for Open Access Workflows for Academic Librarians (OAWAL) [PDF]

open access: yes, 2014
For the past nine months, Graham stone and Jill emery have been promotion OAWAL: Open Access Workflows for Academic Librarians on a blog site, through facebook, through Twitter, and at in-person events in both the US and UK to raise awareness of open ...
Emery, Jill, Stone, Graham
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

ITERA: IDL Tool for Emission-line Ratio Analysis

open access: yes, 2010
We present a new software tool to enable astronomers to easily compare observations of emission line ratios with those determined by photoionization and shock models, ITERA, the IDL Tool for Emission-line Ratio Analysis.
Allen, Mark, Groves, Brent
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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