Results 71 to 80 of about 723,125 (296)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A proposal for incorporating vegetation elements into BIM libraries [PDF]

E3S Web of Conferences
The current trend in the construction industry is shifting towards the implementation of sustainable and green solutions, with vegetative elements playing a significant role.
Halaszova Ivana, Kozlovska Maria
doaj   +1 more source

Special Libraries, July 1925 [PDF]

, 1925
Volume 16, Issue 7https://scholarworks.sjsu.edu/sla_sl_1925/1006/thumbnail ...
Special Libraries Association
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Stories from the walking library [PDF]

, 2014
From August 17 to September 17, 2012, Deirdre Heddon and Misha Myers created and carried a Walking Library, made for the Sideways Arts Festival. Sideways, a festival ‘in the open' and 'on the go', aimed to connect ecology and culture through using the ...
Heddon, Deirdre, Myers, Misha
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Open Access Week 2011 in the Czech Republic (Report)

Liber Quarterly: The Journal of European Research Libraries, 2012
The awareness of open access is slowly rising in the Czech academic environment. Both green open access and gold open access have broken through thanks to Open Access Week, which has for the second time been organized by twelve Czech university libraries,
Pavla Rygelová
doaj   +1 more source

Reading Matters in the Academic Library: Taking the Lead from Public Librarians [PDF]

, 2013
With the increasing virtualization of resources, reference service, and instruction, college students have fewer reasons to visit the academic library, a place they believe lacks relevance in their lives.
Dewan, Pauline
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Dynamic, ecological, accessible and 3D Virtual Worlds-based Libraries using OpenSim and Sloodle along with mobile location and NFC for checking in

International Journal of Interactive Multimedia and Artificial Intelligence, 2012
This paper proposes the implementation of a 3D virtual library, using open platforms such as OpenSimulator and Sloodle, applied to the integration of virtual learning environments.
Rubén González Crespo, Sergio Rios Aguilar, Roberto Ferro-Escobar, Nicolas Torres   +3 more
doaj   +1 more source