Results 81 to 90 of about 717,872 (347)
Reading Matters in the Academic Library: Taking the Lead from Public Librarians [PDF]
, 2013 With the increasing virtualization of resources, reference service, and instruction, college students have fewer reasons to visit the academic library, a place they believe lacks relevance in their lives.
Dewan, Pauline
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Open source repositories: Implications for libraries [PDF]
, 2010 Software that is accepted as “Open source” should comply with 10 conditions which are itinerated in the paper. The paper subsequently describes the application of open source initiatives in the digital library context.
A.N., Zainab
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
MC-TESTER: a universal tool for comparisons of Monte Carlo predictions for particle decays in high energy physics [PDF]
, 2002 Theoretical predictions in high energy physics are routinely provided in the form of Monte Carlo generators. Comparisons of predictions from different programs and/or different initialization set-ups are often necessary.
Barberio +11 more
core +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
, 2015 Fachleute zeigen in übergreifenden Beiträgen und anhand von konkreten Fallbeispielen sowohl aus Deutschland wie aus anderen Teilen Europas, Asiens, Australiens und den USA, wie der ökologische Fußabdruck im Alltag der Bibliothek verringert werden kann und was Nachhaltigkeit für die soziale Verantwortung von Bibliotheken in ihrer Rolle als ...
Sommer, Dorothea +8 more
openaire +1 more source
Diverse diazotrophs are present on sinking particles in the North Pacific Subtropical Gyre. [PDF]
, 2019 Sinking particles transport carbon and nutrients from the surface ocean into the deep sea and are considered hot spots for bacterial diversity and activity.
Collins, James R +6 more
core +1 more source