Results 61 to 70 of about 363,078 (257)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Structure and spectroscopic properties of N,S-coordinating 2-methylsulfanyl-N-[(1H-pyrrol-2-yl)methylidene]aniline methanol monosolvate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The reaction of pyrrole-2-carboxaldehyde and 2-(methylsulfanyl)aniline in refluxing methanol gave an olive-green residue in which yellow crystals of the title compound, C12H12N2S·CH3OH, were grown from slow evaporation of methanol at 263 K.
D. Douglas Richards, M. Trisha C. Ang, Robert McDonald, Matthias Bierenstiel   +3 more
doaj   +1 more source

Process Configuration Studies of Methanol Production via Carbon Dioxide Hydrogenation: Process Simulation-Based Optimization Using Artificial Neural Networks

Energies, 2020
Methanol production via carbon dioxide (CO2) hydrogenation is a green chemical process, which can reduce CO2 emission. The operating conditions for minimum methanol production cost of three configurations were investigated in this work.
Prapatsorn Borisut, Aroonsri Nuchitprasittichai   +1 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Energy, exergy and thermoeconomic analyses for a power-to-green methanol production plant

Energy Nexus
The feasibility of integrating a CCU (Carbon Capture and Utilization) plant into a green methanol production system was studied through detailed energy, exergy, and thermoeconomic analyses from process, economic, and environmental perspectives.
Yungpil Yoo, Sang-Yup Lee, Seok-Ho Seo, Si-Doek Oh, Ho-Young Kwak   +4 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Assessment of Sustainability Indicators for Biodiesel Production

Applied Sciences, 2017
Biodiesel production may provide a sustainable route to reduce environmental pollution caused by fossil fuel consumption. In order to minimize environmental impacts of biodiesel production, the chemical process should be optimized to minimize waste ...
Edith Martinez-Guerra, Veera Gnaneswar Gude   +1 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Feasibility study of renewable e-methanol production: A substitution pathway from blue to green

iEnergy
Producing renewable e-methanol from e-hydrogen and diverse carbon sources is an essential way for clean methanol preparation. Despite this, the technical and economic feasibility of different e-methanols has yet to be thoroughly compared, leaving the ...
Peiyang Li, Jin Lin, Zhipeng Yu, Yingtian Chi, Kai Zhao   +4 more
doaj   +1 more source