Results 91 to 100 of about 2,333,657 (306)

Use of GIS Technology for Distribution of City Forests and Green Open Spaces

open access: yesJurnal Teknologi Informatika & Komputer
Metro City, as one of the urban areas in Indonesia, faces big challenges in managing and maintaining the balance of the urban ecosystem. Green Open Space (RTH) and City Forests have a strategic role in supporting ecosystem sustainability through ...
Nur Zailani, Budi Sutomo
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Kaitan Ruang Terbuka Hijau dengan Kenyamanan Termal Perkotaan [PDF]

open access: yes, 2014
The existence of green open space in urban areas is very important in influencing the conditions of thermal comfort. The objective of this research was to analyze the relationship between green open space and human comfort for the city of Yogyakarta.
Aprihatmoko, F. (Ferdy)   +1 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Planning Strategies for Increasing the Occupancy Rate of Green Open Space Based on Urban Geographic Data in Macau: An Investigation of Ultra-High-Density Cities

open access: yesBuildings
Urban green space can effectively optimize the urban landscape and environment and provide residents with space for daily leisure and recreational activities.
Jitai Li   +4 more
doaj   +1 more source

Sebaran Ruang Terbuka Hijau Jagakarsa [PDF]

open access: yes, 2016
Acceleration in urban development had impact to environment and urban spatial. The increase of physical development and urban infrastructure influence to decreasing quantity of green open space.
rachmawati, N. (nia)
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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