Results 171 to 180 of about 1,826,217 (302)

Development and External Validation of an Efficient Deep Learning Model for Lesion Segmentation and Subtyping of Hepatic Echinococcosis in Ultrasound Imaging

open access: yesHealth Care Science, EarlyView.
We developed a lightweight deep learning framework that integrates frequency‐ and spatial‐domain ultrasound features with segmentation‐assisted classification for hepatic echinococcosis diagnosis. The model outperformed existing state‐of‐the‐art methods in both accuracy and inference speed while requiring substantially fewer computational resources ...
Zhu He   +11 more
wiley   +1 more source

The Relationship Between Street Tree Growth and Projected Pruning and Waste Wood Management Costs

open access: yes, 1993
Total pruning time, waste wood stack time, waste wood yield, and average annual diameter growth rates were determined for four street tree species in Milwaukee. Wisconsin. Two hundred and seventy sample trees in various diameter classes (4-16 inch; 10.
Churack, Patrick L.
core  

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

open access: yesiMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou   +8 more
wiley   +1 more source

Microglial PGC-1α alleviates synaptic damage and cognitive impairments following anesthesia and surgery by suppressing excessive synaptic pruning in aged mice. [PDF]

open access: yesInt J Biol Sci
Wu X   +14 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi   +13 more
wiley   +1 more source

Agronomic and Physiological Aspects of Programmed Cycle Pruning in <i>Coffea arabica</i>. [PDF]

open access: yesPlants (Basel)
Baitelle DC   +13 more
europepmc   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

open access: yesInterdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang   +7 more
wiley   +1 more source

The microglial TREM2 receptor programs hippocampal development in a mouse model of childhood deprivation. [PDF]

open access: yesBrain Behav Immun
Ahmed S   +10 more
europepmc   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

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