Results 71 to 80 of about 1,869,047 (290)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis [PDF]

, 2014
Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes.
Anderson, M, Bailey, P, Barbour, A, Bruxner, T, Campbell, P, Christ, A, Fink, J, Gotley, D, Grimmond, S, Harliwong, I, Hayward, N, Holmes, O, Hussey, D, Idrisoglu, S, Kazakoff, S, Krause, L, Lampe, G, Leonard, C, Loffler, K, Lord, R, Manning, S, Miller, D, Nancarrow, D, Newell, F, Nones, K, Nourbakhsh, E, Nourse, C, Patch, A, Pearson, J, Phillips, W, Quek, K, Quinn, M, Reid, L, Simpson, P, Smithers, B, Tang, Y, Waddell, N, Waddell, N, Watson, D, Wayte, N, Whiteman, D, Wilson, P, Wood, S, Xu, Q   +43 more
core   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

New Sample Preparation Method for Honey Volatiles Fingerprinting Based on Dehydration Homogeneous Liquid–Liquid Extraction (DHLLE)

Molecules, 2018
Qualitative chemical fingerprinting of the honey volatiles by gas chromatography and mass spectrometry (GC-MS) has been an efficient authentication tool that allowed for the classification of the honey botanical origin (strongly related to its medicinal ...
Piotr M. Kuś, Igor Jerković
doaj   +1 more source

Effect of slaughter age between 5 and 14 months on the quality of sheep meat with specific focus on collagen concentration and solubility : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Animal Science at Massey University, Manawatu, New Zealand [PDF]

, 2017
In New Zealand, pasture-raised lamb is considered the highest quality sheep meat product while hogget is a downgraded product considered to be of poorer quality.
Mashele, Grace Arbogast
core  

Green sample preparation strategies for organic/inorganic compounds in environmental samples [PDF]

Current Opinion in Green and Sustainable Chemistry, 2019
A rigorous evaluation of environmental contamination requires constant innovation in analytical approaches to gain early identification and accurate quantification of every substance able to compromise health and well-being, particularly when trace analysis of organic and inorganic contaminants, and their species, in complex environmental samples is ...
Cerutti, Estela Soledad, Pacheco, Pablo Hugo, Gil, Raul Andres, Martinez, Luis Dante   +3 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Automated green sample preparation for quantitative extraction of lipids in different sample matrices

Green Analytical Chemistry
An essential step in all analytical workflows is the quantitative and robust extraction of the molecules of interest. While typical lipid extractions use hazardous solvents from non-renewable sources, in this work, an extraction protocol utilizing green ...
Pia Wittenhofer, Lidia Montero, Oliver J. Schmitz, Sven W. Meckelmann   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Microscopy of a scalable superatom [PDF]

, 2015
Strong interactions can amplify quantum effects such that they become important on macroscopic scales. Controlling these coherently on a single particle level is essential for the tailored preparation of strongly correlated quantum systems and opens up ...
Bloch, Immanuel, Gross, Christian, Hild, Sebastian, Macrì, Tommaso, Schauß, Peter, Zeiher, Johannes   +5 more
core   +3 more sources