Results 61 to 70 of about 7,744,433 (255)

Aerogels and cryogels as green sorbents for organic contaminant extraction and chromatographic analysis

open access: yesSustainable Chemistry for the Environment
In recent years, there has been increasing interest in developing more environmentally friendly analytical methods. In this context, microextraction techniques have gained wider application, and novel materials are being researched as potential ...
Ilektra C. Feida   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Green sample preparation 2023

open access: yesAdvances in Sample Preparation, 2023
Francisco Pena-Pereira   +3 more
doaj   +1 more source

Natural deep eutectic solvents and natural solid biosorbents in microextraction techniques of organic compounds based on chromatographic techniques: A critical review

open access: yesAdvances in Sample Preparation
Analytical chemistry has increasingly focused on the environmental impact of its methods, with significant attention given to green principles in sample preparation. Techniques like Solid-Phase Microextraction (SPME), Micro-Solid-Phase Extraction (µ-SPE),
Eduardo Carasek   +4 more
doaj   +1 more source

A New Calibration Methodology for Quantitative Elemental Analysis of Zeolite Compounds through WD-XRF [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering
Considering the growing need for rapid and accurate analysis of zeolites, X-Ray Fluorescence (XRF) spectrometry is a suitable technique for fast analysis without the need for extensive sample preparation.
Azam Samiei   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Sexual Hormones Determination in Biofluids by In-Vial Polycaprolactone Thin-Film Microextraction Coupled with HPLC-MS/MS

open access: yesMolecules
The in-vial microextraction technique is emerging as an alternative sample treatment, as it integrates sorbent preparation, adsorption, and desorption of analytes in a single device before instrumental analysis.
Francesca Merlo   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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