Results 81 to 90 of about 1,869,047 (290)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
From Few to Many: Observing the Formation of a Fermi Sea One Atom at a Time
Knowing when a physical system has reached sufficient size for its macroscopic properties to be well described by many-body theory is difficult. We investigate the crossover from few to many-body physics by studying quasi one-dimensional systems of ...
Brouzos, I. +5 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In recent years, there has been increasing interest in developing more environmentally friendly analytical methods. In this context, microextraction techniques have gained wider application, and novel materials are being researched as potential ...
Ilektra C. Feida +3 more
doaj +1 more source
A New Calibration Methodology for Quantitative Elemental Analysis of Zeolite Compounds through WD-XRF [PDF]
Considering the growing need for rapid and accurate analysis of zeolites, X-Ray Fluorescence (XRF) spectrometry is a suitable technique for fast analysis without the need for extensive sample preparation.
Azam Samiei +5 more
doaj +1 more source
γ-Ray and Parsec-scale Jet Properties of a Complete Sample of Blazars From the Mojave Program [PDF]
We investigate the Fermi Large Area Telescope γ-ray and 15 GHz Very Long Baseline Array radio properties of a joint γ-ray and radio-selected sample of active galactic nuclei (AGNs) obtained during the first 11 months of the Fermi mission (2008 August 4 ...
Lister, M. L. +2 more
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Analytical chemistry has increasingly focused on the environmental impact of its methods, with significant attention given to green principles in sample preparation. Techniques like Solid-Phase Microextraction (SPME), Micro-Solid-Phase Extraction (µ-SPE),
Eduardo Carasek +4 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The in-vial microextraction technique is emerging as an alternative sample treatment, as it integrates sorbent preparation, adsorption, and desorption of analytes in a single device before instrumental analysis.
Francesca Merlo +5 more
doaj +1 more source

