Results 101 to 110 of about 1,869,047 (290)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

SPME as a green sample-preparation technique for the monitoring of phytocannabinoids and endocannabinoids in complex matrices. [PDF]

J Pharm Anal, 2023
Woźniczka K, Konieczyński P, Plenis A, Bączek T, Roszkowska A.   +4 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Applying novel economic simple green sample preparation procedures on natural and industrial specimens for chromatographic determination of insecticidal residues. [PDF]

Sci Rep, 2023
Hegazy AM, Mahmoud HM, Elsayed MA, Ali NW, Abdelfatah RM.   +4 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Trace Metal Element Analysis in Some Seafood in the Coastal Zone of the Red River (Ba Lat Estuary, Vietnam) by Green Sample Preparation and Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). [PDF]

J Anal Methods Chem, 2021
Da Le N, Ha Hoang TT, Phung VP, Nguyen TL, Duong TT, Dinh LM, Huong Pham TM, Binh Phung TX, Nguyen TD, Duong TN, Hanh Le TM, Le PT, Quynh Le TP.   +12 more
europepmc   +1 more source

Greenness of official sample preparation standard methods

Chemistry International
GREENNESS OF OFFICIAL SAMPLE PREPARATION STANDARD METHODS Chemistry international (Rights reserved) (-) Greenness of official sample preparation standard methods / Psillakis, Elefteria (Rights reserved) (-)
Psillakis, Elefteria, Chisvert, Alberto, Cagliero, Cecilia, Ozkan, Sibel A., Segundo, Marcela, Mester, Zoltan   +5 more
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Analytical Green Star Area for Sample Preparation (AGSA‐Prep) as a Comprehensive and Practice‐Oriented Metric

Analytical Science Advances
Sample preparation is a critical, yet often environmentally burdensome, step in analytical chemistry. While Green Sample Preparation principles aim to mitigate this impact, existing assessment tools such as AGREEprep offer room for improvement in the ...
Fotouh R. Mansour, Reem H. Obaydo, Marcello Locatelli, Alaa Bedair   +3 more
doaj   +1 more source

Molecularly imprinted polymers in solid-phase microextraction: Enhancing the analysis of pharmaceutical compounds across diverse sample matrices

Journal of Pharmaceutical and Biomedical Analysis Open
The biomedicine scientific field has made continuous progress, introducing various pharmaceutical compounds to enhance human life. While these advancements bring benefits, the unregulated use of these compounds raises concerns, particularly regarding ...
Rafael Oliveira Martins, Almir Custodio Batista Junior, Camila Cíntia Sousa Melo Brito, Yuri Arrates Rocha, Andréa Rodrigues Chaves   +4 more
doaj   +1 more source