Results 111 to 120 of about 169 (164)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

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Sample preparation in a green perspective

2023
Orfeas-Evangelos Plastiras, Emanuela Gionfriddo, Victoria F. Samanidou   +2 more
openaire   +3 more sources

Carbonaceous Materials in Green Sample Preparation

2023
Owing to their fascinating properties such as high surface area-to-volume ratios, porosity, chemical/thermal stability, and conductivity, carbonaceous materials are considered to be one of the excellent classes of adsorbent/sorbent materials and have led to significant advancements in the field of analytical chemistry.
Arpana Agrawal, Chaudhery Ghazanfar Hussain, Rüstem Keçili, Chaudhery Mustansar Hussain   +3 more
openaire   +1 more source

Ionic Liquids in Green Sample Preparation

2023
Ionic liquids are molten salts with melting points at or below 100 °C. They are a very versatile class of compounds with a chemical structure that can be tuned to achieve the desired physicochemical and solvation properties. For this reason, they have found wide application in the sample preparation field in both liquid- and solid-phase extraction.
Mastellone, G., Marengo, A., Sgorbini, B., Rubiolo, P., Cagliero, C.   +4 more
openaire   +2 more sources

Miniaturization and Automation in Green Sample Preparation

2023
Amongst the different steps of any analytical procedure, sample preparation is considered to be one of the most critical. Currently, efforts are centred in the development of miniaturized extraction techniques, which make use of efficient extraction sorbents/solvents and reduce organic solvent and/or energy consumption, following the principles of ...
G. Jiménez-Skrzypek, J. González-Sálamo, J. Hernández-Borges   +2 more
openaire   +1 more source

Natural Sorbents in Green Sample Preparation

2023
The evolution of the sample treatment step towards the incorporation of the principles of Green Chemistry inevitably involves the use of materials that are sustainable from an environmental point of view. One of the most important advances in recent years is the use of natural materials as sorbent phases in microextraction processes.
Jaime Millán-Santiago, Guillermo Lasarte-Aragonés, M. Laura Soriano, Angela I. López-Lorente, Rafael Lucena, Soledad Cárdenas   +5 more
openaire   +1 more source