Results 121 to 130 of about 7,744,433 (255)

Sample of lime green, turquoise, brown and light green floral furnishing fabric.

open access: yes, 2010
Sample of lime green, turquoise, brown and light green floral furnishing fabric.. Date: 1972 (circa) - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

An introduction to coal preparation

open access: yes, 1985
FOREWORDThe Coal Preparation Society of N.S.W. has been conducting\ua0preliminary and advanced courses in coal preparation for many\ua0years. The preliminary courses are held each year in three or four\ua0centres in coalfields areas and in Sydney, most ...
Coal Preparation Society of N.S.W.
core  

INNOVATIVE PROCESS LINE FOR MATERIAL SAMPLE PREPARATION

open access: yes
. The successful establishment and sustainable development of mining enterprises depends on a number of factors, including geological research, management of mineral extraction and processing processes, and sample preparation technology.
O. V. Fedoskina   +4 more
core   +1 more source

Advances in miniaturized liquid sample preparation techniques for environmental analysis: A special look towards green solvents and automation

open access: yesJournal of Chromatography Open
The continuous advancements in agricultural and industrial practices have led to the widespread introduction of various chemicals across key production sectors.
Rafael Oliveira Martins   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Sample of Fabric with Blue and Green Checkerboard Pattern

open access: yes, 2010
Sample of Fabric with Blue and Green Checkerboard Pattern - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

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