Results 141 to 150 of about 376,652 (301)
Solid Phase Peptide Synthesis (SPPS) is the preferred technique for synthesizing bioactive peptides. However, traditional SPPS generates significant waste and employs hazardous solvents like DMF and DCM.
Giovanni Vivenzio +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Optimizing a Simple Natural Dye Production Method for Dye-Sensitized Solar Cells: Examples for Betalain (Bougainvillea and Beetroot Extracts) and Anthocyanin Dyes [PDF]
We present a study about the sensitizers extracted from natural resources. This paper focuses on how to select, extract and characterize natural dyes, giving some guides to establish a protocol for the whole process of fabricating and using these dyes ...
Ariza Camacho, María Jesús +1 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Background The substantially operated analytical instruments dealing in the area of analytical chemistry are traditional methods like high-performance liquid chromatography (HPLC) and gas chromatography (GC).
Meshwa Mehta +2 more
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Good Bulbs, Bad Jobs: Workers and Conditions Behind Your New Compact Fluorescent [PDF]
The study highlights labor violations at a Xiamen Topstar Lighting Co. Ltd. factory, a joint venture in which GE has a stake. The report recommends that GE follow its own policies and ensure that its bulbs are made in a way that does not compromise the ...
Policy Matters Ohio
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

