Results 91 to 100 of about 3,299,126 (295)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

SU(2)-invariant reduction of the 3+1 dimensional Ashtekar's gravity

open access: yes, 1997
We consider a space-time with spatial sections isomorphic to the group manifold of SU(2). Triad and connection fluctuations are assumed to be SU(2)-invariant. Thus, they form a finite dimensional phase space.
Ashtekar A   +14 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pattern of Public Green Open Space in Tembalang Settlement, Semarang

open access: yesE3S Web of Conferences, 2018
Public green open space is the use of green open space that is focused on the public interest and is under the ownership and management of local government or local comunity.
Diah Intan Kusumo Dewi   +3 more
doaj   +1 more source

Green exports and the global product space: Prospects for EU industrial policy [PDF]

open access: yes
We test if and where industrial policy to promote â??greenâ?? industry development can improve competitiveness in export markets. Proponents of â??green growthâ?? have argued that domestic promotion of â??greenâ??
Georg Zachmann, Mark Huberty
core   +1 more source

On the Global Hadamard form for the Green Function in Schwarzschild space-time

open access: yes, 2020
The retarded Green function of a wave equation on a 4-dimensional curved background space-time is a (generalized) function of two space-time points and diverges when these are connected by a null geodesic.
Casals, Marc, Nolan, Brien
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Towards complex(rational) powers of free fields, generalized $\beta\gamma$ systems and non-polynomial quantum field theory

open access: yes, 1994
The $\beta\gamma$ system is generalized by complex(rational) powers of the fields, which leads to a corresponding extension on the Fock space. Two different approaches to compute the Green functions of the physical operators are proposed.
Andreev, Oleg
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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