Results 101 to 110 of about 743,434 (310)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The CO Quality Level Of Green Open Space (Case Study Of Jagakarsa District, South Jakarta)
Journal of Natural Resources and Environmental Management, 2022 Green Open Space serves indirectly to improve the level of public health. One of the sub-districts in South Jakarta is Jagakarsa is a potential area in the development of Green Open Space. Green plants as one of the elements of Green Open Space have the
Purnomosutji Dyah Prinajati
doaj
Enabling rural broadband via TV "white space"
, 2012 The use of multiple frequency bands within a wireless network allows the advantages of each band to be exploited. In this paper we discuss how HopScotch, a rural wireless broadband access test bed running in the Scottish Highlands and Islands, uses both ...
Weiss, Stephan +9 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Evidence on the relationship between green and blue spaces and mental health in regional areas of Australia is limited. This study assessed associations between green space, blue space, green-blue space (GBS), and psychological distress in regional ...
Biddle, Stuart J.H. +3 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Pattern of Public Green Open Space in Tembalang Settlement, Semarang
E3S Web of Conferences, 2018 Public green open space is the use of green open space that is focused on the public interest and is under the ownership and management of local government or local comunity.
Diah Intan Kusumo Dewi +3 more
doaj +1 more source