Results 101 to 110 of about 3,299,126 (295)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Research on the collaborative mechanism between site selection optimization model and control of green space planning under the background of urban renewal

Discover Sustainability
As a part of integrated urban ecosystems, green space is an important target of urban renewal planning. In the process of urban renewal of green space, it is difficult to control the special planning for green space systems, and the scale of urban public
Xiangyun Li, Desheng Dai, Jingwen Dong, Kaili Hu   +3 more
doaj   +1 more source

Evaluation of Green Open Space Management Program in Gresik Regency Based on Cipp Evaluation Model [PDF]

, 2016
Rapid industrialization gives direct impact on the environmental conditions in Gresik Regency. One attempt to maintain the balance of nature due to the rapid industrialization and rapid urban development is providing enough green open space (GOS) through
Suryadi, S. (Suryadi), Wati, S. (Susilo), Wijaya, A. F. (Andy)   +2 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Dual Bosonic Thermal Green Function and Fermion Correlators of the Massive Thirring Model at a Finite Temperature

, 2007
The Euclidian thermal Green function of the two-dimensional (2D) free massless scalar field in coordinate space is written as the real part of a complex analytic function of a variable that conformally maps the infinite strip ...
Marino, E. C., Mondaini, Leonardo
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Rigorous mean field model for CPA: Anderson model with free random variables

, 1994
A model of a randomly disordered system with site-diagonal random energy fluctuations is introduced. It is an extension of Wegner's $n$-orbital model to arbitrary eigenvalue distribution in the electronic level space.
A. M. Khorunzhy, B. Kümmerer, B. Velický, D. V. Taylor, D. Voiculescu, D. Voiculescu, D. Voiculescu, D. Voiculescu, D. Voiculescu, E. N. Economou, E. P. Wigner, F. Wegner, H. Bercovici, H. Maassen, I. M. Lifshitz, L. A. Pastur, L. Arnold, P. Lloyd, P. Neu, P. Neu, P. Neu, P. Soven, P. W. Anderson, Peter Neu, R. L. Hudson, R. Speicher, R. Speicher, R. Speicher, Roland Speicher, U. Frisch   +29 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Three-point Green function of massless QED in position space to lowest order

, 2008
The transverse part of the three-point Green function of massless QED is determined to the lowest order in position space. Taken together with the evaluation of the longitudinal part in arXiv:0803.2630, this gives a relation for QED which is analogous to
Fradkin E S, Fradkin E S Palchik M Y, Indrajit Mitra, Mitra I, Palchik M Ya   +4 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source