Results 31 to 40 of about 207,873 (208)

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita, Norma Candelaria López Santiago, Claudia Maria García Cuellar, Karla Maldonado Silva, Nancy Reynoso Noverón, Leticia Hernández Cadena   +5 more
wiley   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source

Green space exposure and blood DNA methylation at birth and in childhood – A multi-cohort study

Environment International
Green space exposure has been associated with improved mental, physical and general health. However, the underlying biological mechanisms remain largely unknown.
Sofia Aguilar-Lacasaña, Irene Fontes Marques, Montserrat de Castro, Payam Dadvand, Xavier Escribà, Serena Fossati, Juan R González, Mark Nieuwenhuijsen, Rossella Alfano, Isabella Annesi-Maesano, Sonia Brescianini, Kimberley Burrows, Lucinda Calas, Ahmed Elhakeem, Barbara Heude, Amy Hough, Elena Isaevska, Vincent W V Jaddoe, Deborah A Lawlor, Genevieve Monaghan, Tim Nawrot, Michelle Plusquin, Lorenzo Richiardi, Aidan Watmuff, Tiffany C. Yang, Martine Vrijheid, Janine F Felix, Mariona Bustamante   +27 more
doaj   +1 more source

Exposure to natural environments during pregnancy and birth outcomes in 11 European birth cohorts

Environment International, 2022
Research suggests that maternal exposure to natural environments (i.e., green and blue spaces) promotes healthy fetal growth. However, the available evidence is heterogeneous across regions, with very few studies on the effects of blue spaces. This study
Maria Torres Toda, Demetris Avraam, Timothy James Cadman, Serena Fossati, Montserrat de Castro, Audrius Dedele, Geoffrey Donovan, Ahmed Elhakeem, Marisa Estarlich, Amanda Fernandes, Romy Gonçalves, Regina Grazuleviciene, Jennifer R. Harris, Margreet W Harskamp-van Ginkel, Barbara Heude, Jesús Ibarluzea, Carmen Iñiguez, Vincent WV Jaddoe, Deborah Lawlor, Aitana Lertxundi, Johanna Lepeule, Rosemary McEachan, Giovenale Moirano, Johanna LT Nader, Anne-Marie Nybo Andersen, Marie Pedersen, Costanza Pizzi, Theano Roumeliotaki, Susana Santos, Jordi Sunyer, Tiffany Yang, Marina Vafeiadi, Tanja GM Vrijkotte, Mark Nieuwenhuijsen, Martine Vrijheid, Maria Foraster, Payam Dadvand   +36 more
doaj   +1 more source

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Effects of Prenatal Exposure to Ozone, Heatwave and Green Space on Neonatal Congenital Heart Disease: A Case-Control Study in Eastern China

Toxics
Congenital heart disease (CHD) is the most prevalent birth defect. Ozone and heatwave exposure during pregnancy could increase the risk of adverse birth outcomes. Green space might be associated with beneficial birth outcomes.
Weizhe Zhang, Tiezheng Li, Leiyu Shi, Die Li, Mary A. Fox   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A protocol of comprehensive assessment of exposure to greenspace in school children

MethodsX, 2021
Evidence on a comprehensive greenspace exposure assessment on primary school children is scarce yet. Therefore, we aimed to assess a comprehensive greenspace exposure on primary school children and their behavioral function. We assessed different aspects
Hamideh Ebrahimi Aval, Masoumeh Hashemian, Mohammad Miri   +2 more
doaj   +1 more source