ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
The Effect of Environmental Information Disclosure on Green Total Factor Productivity: Evidence from Quasi-Natural Experiments on Cities in China [PDF]
Xiangyan Meng +3 more
openalex +1 more source
Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao +10 more
wiley +1 more source
Local Government Debt and Green Total Factor Productivity-Empirical Evidence from Chinese Cities. [PDF]
Mao K, Failler P.
europepmc +1 more source
Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye +19 more
wiley +1 more source
Spatial Spillover Effects of Resource Misallocation on the Green Total Factor Productivity in Chinese Agriculture. [PDF]
Hu J, Zhang X, Wang T.
europepmc +1 more source
This study investigates the impact of various post‐processing methods (filtration, sonication, dialysis, and heating) on lipid nanoparticles produced using microfluidics. The nanoparticles are designed for efficient delivery of miRNA into cells. The work highlights how processing conditions influence nanoparticle stability and quality, providing ...
Alicja Kosik‐Kozioł +8 more
wiley +1 more source
The Effect of Farmland Transfer on Agricultural Green Total Factor Productivity: Evidence from Rural China. [PDF]
Ma G, Dai X, Luo Y.
europepmc +1 more source
Can FDI Facilitate Green Total Factor Productivity in China?-Evidence from Regional Diversity [PDF]
Jialu You, Hang Xiao
openalex +1 more source
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang +9 more
wiley +1 more source

