Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Transformational Leadership Behaviors as Catalyst to Inclusive Leadership: A Mixed Methods Study on Leadership and Work Experiences of Transgender Employees in the Federal Government [PDF]
Diversity and inclusion have been part of leadership research since the early 1980s. In 2011, President Obama signed Executive Order 13583 “Establishing A Coordinated Government-Wide Initiative to Promote Diversity and Inclusion in the Federal Workforce”
Rosa, Yasmin A.
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Developing leadership that matters: Transformational leadership
Highlights of this Working Paper Brief • Defines Transformational Leadership (TL). • Presents research on the positive effects of TL.
Chua, Paul Meng Huat +1 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This study aims to determine and analyze the effect of green transformational leadership on green employee performance mediated by green work engagement in heavy equipment companies in Indonesia. The method used in this research is descriptive quantitative method.
Indira Puspa Gustiah +1 more
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Abstract We used the resource-based view and the ability-motivation-opportunity theory to analyze the connections between green transformational leadership, green innovation, and environmental performance as they relate to green human resource management.
Jory Usprech, Graham Palmert
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A study examining the use of transformational leadership practices for teacher development [PDF]
Plan BThe purpose of this study was to identify the personal qualities of good teachers as identified by teachers, students and researchers, and to determine whether transformational leadership practices can help develop these desirable personal ...
Button, Barbara
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