Results 111 to 120 of about 181,465 (294)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Green investment strategies: a positive force in cities [PDF]

open access: yes
Deterioration of urban neighborhoods is known to induce out migration, but how well do public investments to reverse decline actually work? To evaluate Philadelphia’s greening investment, researchers measured property buyers’ willingness to pay more—and ...
Carolyn R. Brown   +2 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Improving the Assessment of the Environmental Indicators of Investment Projects Based on the Public-Private Partnership

open access: yesBaltic Journal of Real Estate Economics and Construction Management, 2015
Implementation of environmentally significant activities is often associated with the need to attract significant investment from different sources, both public and private.
Malakhova Tatiana N.   +2 more
doaj   +1 more source

Green heritage, green history and green planning

open access: yes, 2021
The value of historical districts, especially in large urban contexts, is a complex issue. The theoretical debate on the extension of the heritage concept goes back to the International Conventions of The Hague (1954) and Paris (1972) and, in Italy, to the Franceschini Commission of Inquiry, and has recently even reached the hypothesis of "tout ...
Nerantzia Tzortzi, Maria Stella Lux
openaire   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

The Common Agricultural Policy and the Next EU Budget. Bertelsmann Stiftung Reflection Paper No.2: Preparing for the Multiannual Financial Framework after 2020. Paper prepared for Expert Workshop “CAP and the next MFF” Berlin, Federal Foreign Office, 30 March 2017 [PDF]

open access: yes, 2017
The Common Agricultural Policy (CAP) was set up in a time when (a) the memory about post-war food shortage was fresh, (b) Europe was a large net importer of agricultural products, (c) agricultural production was still highly labour-intensive, (d) food ...
von Cramon-Taubadel, Stephan
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Arctic greening associated with lengthening growing seasons in Northern Alaska

open access: yesEnvironmental Research Letters, 2019
Many studies have reported that the Arctic is greening; however, we lack an understanding of the detailed patterns and processes that are leading to this observed greening.
Kyle A Arndt   +8 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

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